Skip to main content

Research Repository

Advanced Search

All Outputs (440)

The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study (2017)
Journal Article
Currow, D. C., Dal Grande, E., Sidhu, C., Ekström, M., & Johnson, M. J. (2017). The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study. European respiratory journal, 50(3), Article 1700558. https://doi.org/10.1183/13993003.00558-2017

Obesity is an independent risk factor for chronic breathlessness and should be assessed in people with this symptom.

Prescribing non-opioid drugs in end-stage kidney disease (2017)
Journal Article
Wilcock, A., Charlesworth, S., Twycross, R., Waddington, A., Worthington, O., Murtagh, F. E., …Kotlinska-Lemieszek, A. (2017). Prescribing non-opioid drugs in end-stage kidney disease. Journal of pain and symptom management, 54(5), 776-787. https://doi.org/10.1016/j.jpainsymman.2017.08.014

Palliative care services are increasingly involved in the care of patients with chronic kidney disease, either alone or as a comorbid condition. Because renal impairment often changes the pharmacokinetic and/or pharmacodynamic effects of a drug, this... Read More about Prescribing non-opioid drugs in end-stage kidney disease.

Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia (2017)
Journal Article
Laoire, Á. N., & Murtagh, F. E. (2018). Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia. BMJ supportive & palliative care, 8(4), 400-410. https://doi.org/10.1136/bmjspcare-2017-001359

Background Critical limb ischaemia (CLI) is a severe manifestation of peripheral arterial disease, characterised by chronic ischaemic rest pain, ulcers or gangrene. Management of ischaemic pain is challenging in patients with no options for revascula... Read More about Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia.

Contributions of a hand-held fan to self-management of chronic breathlessness (2017)
Journal Article
Luckett, T., Phillips, J., Johnson, M. J., Farquhar, M., Swan, F., Assen, T., …Booth, S. (2017). Contributions of a hand-held fan to self-management of chronic breathlessness. European respiratory journal, 50(2), Article 1700262. https://doi.org/10.1183/13993003.00262-2017

© ERS 2017. This study explored the benefits of a hand-held fan as perceived by patients with chronic breathlessness and their carers. A secondary multimethod analysis was conducted of interview data collected in three clinical trials. Two researcher... Read More about Contributions of a hand-held fan to self-management of chronic breathlessness.

Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients (2017)
Journal Article
Mather, H., Guo, P., Firth, A., Davies, J. M., Sykes, N., Landon, A., & Murtagh, F. E. (2018). Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients. Palliative medicine, 32(2), 404-412. https://doi.org/10.1177/0269216317727157

© 2017, © The Author(s) 2017. Background: Phase of Illness describes stages of advanced illness according to care needs of the individual, family and suitability of care plan. There is limited evidence on its association with other measures of sympto... Read More about Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients.

Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting (2017)
Journal Article
Digges, M., Hussein, A., Wilcock, A., Crawford, G. B., Boland, J. W., Agar, M. R., …Johnson, M. J. (2018). Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting. Journal of palliative medicine, 21(1), 37-43. https://doi.org/10.1089/jpm.2017.0159

Background Haloperidol is widely prescribed as an anti-emetic in patients receiving palliative care, but there is limited evidence to support and refine its use. Objective To explore the immediate and short-term net clinical effects of haloperidol wh... Read More about Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting.

Towards an understanding of how appraisal of doctors produces its effects: a realist review (2017)
Journal Article
Brennan, N., Bryce, M., Pearson, M., Wong, G., Cooper, C., & Archer, J. (2017). Towards an understanding of how appraisal of doctors produces its effects: a realist review. Medical Education, 51(10), 1002-1013. https://doi.org/10.1111/medu.13348

© 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education Context: Revalidation was launched in the UK to provide assurances to the public that doctors are up to date and fit to practice. Appraisal is a fundamental compone... Read More about Towards an understanding of how appraisal of doctors produces its effects: a realist review.

Care of the dying : a qualitative exploration of foundation year doctors’ experiences (2017)
Journal Article
Redman, M., Pearce, J., Gajebasia, S., Johnson, M., & Finn, G. (2017). Care of the dying : a qualitative exploration of foundation year doctors’ experiences. Medical Education, 51(10), 1025-1036. https://doi.org/10.1111/medu.13358

Context Foundation Year doctors (FYs), who are newly qualified, are expected to provide care for dying patients. Experiences at this early mandatory stage of training may form the foundation for future encounters, but little is documented about wha... Read More about Care of the dying : a qualitative exploration of foundation year doctors’ experiences.

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol (2017)
Journal Article
Currow, D., Watts, G. J., Johnson, M., McDonald, C. F., Miners, J. O., Somogyi, A. A., …Ekström, M. (2017). A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol. BMJ open, 7(7), 1-18. https://doi.org/10.1136/bmjopen-2017-018100

© Article author(s). Introduction Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended-release (ER) o... Read More about A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.

Influence of opioids on immune function in patients with cancer pain: from bench to bedside (2017)
Journal Article
Boland, J. W., & Pockley, A. G. (in press). Influence of opioids on immune function in patients with cancer pain: from bench to bedside. British Journal of Pharmacology, 175(14), 2726-2736. https://doi.org/10.1111/bph.13903

In patients with cancer, opioids are principally used for the management of acute surgical and chronic cancer-related pain. However, opioids have many non-analgesic effects, including direct and indirect effects on cancer cells and on anti-tumour imm... Read More about Influence of opioids on immune function in patients with cancer pain: from bench to bedside.

Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review (2017)
Journal Article
Papoutsi, C., Mattick, K., Pearson, M., Brennan, N., Briscoe, S., & Wong, G. (2017). Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review. The journal of antimicrobial chemotherapy, 72(9), 2418-2430. https://doi.org/10.1093/jac/dkx194

Background Antimicrobial resistance has led to widespread implementation of interventions for appropriate prescribing. However, such interventions are often adopted without an adequate understanding of the challenges facing doctors-in-training as key... Read More about Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review.

“Go make your face known”: Collaborative working through the lens of personal relationships (2017)
Journal Article
King, N., Bravington, A., Brooks, J., Melvin, J., & Wilde, D. (2017). “Go make your face known”: Collaborative working through the lens of personal relationships. International journal of integrated care, 17(4), Article 3. https://doi.org/10.5334/ijic.2574

© 2017 The Author(s). Background: Collaborative working between professionals is a key component of integrated care. The academic literature on it largely focuses either on integration between health and social care or on the dynamics of power and id... Read More about “Go make your face known”: Collaborative working through the lens of personal relationships.

Determinants of hospital death in haematological cancers: findings from a qualitative study (2017)
Journal Article
McCaughan, D., Roman, E., Smith, A. G., Garry, A., Johnson, M., Patmore, R., …Howell, D. A. (2018). Determinants of hospital death in haematological cancers: findings from a qualitative study. BMJ supportive & palliative care, 8(1), 78-86. https://doi.org/10.1136/bmjspcare-2016-001289

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. Objectives: Current UK health policy promotes enabling people to die in a place they choose, which for most is home. Despite this, patients with haema... Read More about Determinants of hospital death in haematological cancers: findings from a qualitative study.

Cognitive-emotional interventions for breathlessness in adults with advanced diseases (2017)
Journal Article
Bolzani, A., Rolser, S. M., Kalies, H., Maddocks, M., Rehfuess, E., Hutchinson, A., …Bausewein, C. (2017). Cognitive-emotional interventions for breathlessness in adults with advanced diseases. The Cochrane database of systematic reviews, 2017(6), Article CD012682. https://doi.org/10.1002/14651858.CD012682

© 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects and safety of interventions targeting cognition, emotion or both a... Read More about Cognitive-emotional interventions for breathlessness in adults with advanced diseases.

Respiratory interventions for breathlessness in adults with advanced diseases (2017)
Journal Article
Bolzani, A., Rolser, S. M., Kalies, H., Maddocks, M., Rehfuess, E., Swan, F., …Bausewein, C. (2017). Respiratory interventions for breathlessness in adults with advanced diseases. The Cochrane database of systematic reviews, 2017(6), Article CD012683. https://doi.org/10.1002/14651858.CD012683

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects and safety of interventions targeting respiration as the predominant underlying mechanism of effect to relieve breathlessness in adults suff... Read More about Respiratory interventions for breathlessness in adults with advanced diseases.

The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey (2017)
Journal Article
Chen, H., Currow, D. C., Dunn, L., Johnson, M. J., Macleod, U., & Allgar, V. (2018). The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey. Palliative medicine, 32(2), 357-365. https://doi.org/10.1177/0269216317711825

Background: Previous work shows that more affluent patients with cancer are more likely to die at home, whereas those dying from non-cancer conditions are more likely to die in hospital. Family caregivers are an important factor in determining place... Read More about The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey.

Time to improve informed consent for dialysis: an international perspective (2017)
Journal Article
Murtagh, F. E., Brennan, F., Stewart, C., Burgess, H., Davison, S. N., Moss, A. H., …Brown, M. (2017). Time to improve informed consent for dialysis: an international perspective. Clinical journal of the American Society of Nephrology, 12(6), 1001-1009. https://doi.org/10.2215/CJN.09740916

The literature reveals that current nephrology practice in obtaining informed consent for dialysis falls short of ethical and legal requirements. Meeting these requirements represents a significant challenge, especially because the benefits and risks... Read More about Time to improve informed consent for dialysis: an international perspective.

Improving Hospital at Home for frail older people: insights from a quality improvement project to achieve change across regional health and social care sectors (2017)
Journal Article
Pearson, M., Hemsley, A., Blackwell, R., Pegg, L., & Custerson, L. (2017). Improving Hospital at Home for frail older people: insights from a quality improvement project to achieve change across regional health and social care sectors. BMC health services research, 17(1), Article ARTN 387. https://doi.org/10.1186/s12913-017-2334-9

© 2017 The Author(s). Background: Against a background of rising numbers of frail older people, there is a need to improve quality and safety of services whilst containing costs. Improving patient outcomes requires change across hospital and communit... Read More about Improving Hospital at Home for frail older people: insights from a quality improvement project to achieve change across regional health and social care sectors.