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All Outputs (461)

Making sense of evidence: using research training to promote organisational change (2017)
Journal Article
Wilkinson, K., Boyd, K., Pearson, M., Farrimond, H., Lang, I. A., Fleischer, D., Poole, A., Ralph, N., & Rappert, B. (2019). Making sense of evidence: using research training to promote organisational change. Police Practice and Research, 20(5), 511-529. https://doi.org/10.1080/15614263.2017.1405266

Many have argued that the development of evidence-based policing (EBP) depends on those in law enforcement agencies receiving appropriate training in research methodologies and data analysis. Despite this, there are few detailed accounts of such trai... Read More about Making sense of evidence: using research training to promote organisational change.

Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries (2017)
Journal Article
Higginson, I. J., Bennett, E., Daveson, B. A., Cooper, F., Morrison, R. S., Yi, D., de Wolf-Linder, S., Meier, D., Dzingina, M., Smith, M., Ellis-Smith, C., Ryan, K., Evans, C., McQuillan, R., Ferguson, T., Normand, C., Henson, L., Johnston, B. M., Murtagh, F. E., Kaler, P., …Wei, G. (2017). Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries. BMC Geriatrics, 17(1), https://doi.org/10.1186/s12877-017-0648-4

© 2017 The Author(s). Background: Achieving choice is proposed as a quality marker. But little is known about what influences preferences especially among older adults. We aimed to determine and compare, across three countries, factors associated wit... Read More about Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries.

Collaborative action for person-centred coordinated care (P3C): An approach to support the development of a comprehensive system-wide solution to fragmented care (2017)
Journal Article
Lloyd, H. M., Pearson, M., Sheaff, R., Asthana, S., Wheat, H., Sugavanam, T. P., Britten, N., Valderas, J., Bainbridge, M., Witts, L., Westlake, D., Horrell, J., & Byng, R. (2017). Collaborative action for person-centred coordinated care (P3C): An approach to support the development of a comprehensive system-wide solution to fragmented care. Health research policy and systems, 15(1), Article 98. https://doi.org/10.1186/s12961-017-0263-z

Background
Fragmented care results in poor outcomes for individuals with complexity of need. Person-centred coordinated care (P3C) is perceived to be a potential solution, but an absence of accessible evidence and the lack of a scalable ‘blue print’... Read More about Collaborative action for person-centred coordinated care (P3C): An approach to support the development of a comprehensive system-wide solution to fragmented care.

Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease (2017)
Journal Article
Johnson, M. J., Jamali, A., Ross, J., Fairhurst, C., Boland, J., Reigada, C., Hart, S. P., Grande, G., Currow, D. C., Wells, A. U., Papadopoulos, T., Bajwah, S., Bland, J. M., & Yorke, J. (2018). Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease. Thorax, 73(9), 880-883. https://doi.org/10.1136/thoraxjnl-2017-210911

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. The inter-rater/test-retest reliability and construct validity... Read More about Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease.

Conference presentation in palliative medicine: Predictors of subsequent publication (2017)
Journal Article
Hanchanale, S., Kerr, M., Ashwood, P., Curran, E., Ekstrom, M., Allen, S., Currow, D., & Johnson, M. J. (2018). Conference presentation in palliative medicine: Predictors of subsequent publication. BMJ Supportive & Palliative Care, 8(1), 73-77. https://doi.org/10.1136/bmjspcare-2017-001425

© 2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article). All rights reserved. Objectives Concerns have been raised about poor-quality palliative care research and low publication rate from conference abstrac... Read More about Conference presentation in palliative medicine: Predictors of subsequent publication.

Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis (2017)
Journal Article
Verberkt, C. A., van den Beuken-van Everdingen, M. H., Schols, J. M., Datla, S., Dirksen, C. D., Johnson, M. J., van Kuijk, S. M., Wouters, E. F., & Janssen, D. J. (2017). Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis. European respiratory journal, 50(5), 1701153. https://doi.org/10.1183/13993003.01153-2017

Background: Previous studies have shown that opioids can reduce chronic breathlessness in advanced disease. However, physicians remain reluctant to prescribe opioids for these patients, commonly due to fear of respiratory adverse effects. Aim: To sys... Read More about Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis.

What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death (2017)
Journal Article
Bone, A. E., Gomes, B., Etkind, S. N., Verne, J., Murtagh, F. E., Evans, C. J., & Higginson, I. J. (2018). What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death. Palliative medicine, 32(2), 329-336. https://doi.org/10.1177/0269216317734435

© 2017, © The Author(s) 2017. Background: Population ageing represents a global challenge for future end-of-life care. Given new trends in place of death, it is vital to examine where the rising number of deaths will occur in future years and implica... Read More about What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death.

The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study (2017)
Journal Article
Currow, D. C., Dal Grande, E., Sidhu, C., Ekström, M., & Johnson, M. J. (2017). The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study. European respiratory journal, 50(3), Article 1700558. https://doi.org/10.1183/13993003.00558-2017

Obesity is an independent risk factor for chronic breathlessness and should be assessed in people with this symptom.

Prescribing non-opioid drugs in end-stage kidney disease (2017)
Journal Article
Wilcock, A., Charlesworth, S., Twycross, R., Waddington, A., Worthington, O., Murtagh, F. E., Beavis, J., King, S., Mihalyo, M., & Kotlinska-Lemieszek, A. (2017). Prescribing non-opioid drugs in end-stage kidney disease. Journal of pain and symptom management, 54(5), 776-787. https://doi.org/10.1016/j.jpainsymman.2017.08.014

Palliative care services are increasingly involved in the care of patients with chronic kidney disease, either alone or as a comorbid condition. Because renal impairment often changes the pharmacokinetic and/or pharmacodynamic effects of a drug, this... Read More about Prescribing non-opioid drugs in end-stage kidney disease.

Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia (2017)
Journal Article
Laoire, Á. N., & Murtagh, F. E. (2018). Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia. BMJ supportive & palliative care, 8(4), 400-410. https://doi.org/10.1136/bmjspcare-2017-001359

Background Critical limb ischaemia (CLI) is a severe manifestation of peripheral arterial disease, characterised by chronic ischaemic rest pain, ulcers or gangrene. Management of ischaemic pain is challenging in patients with no options for revascula... Read More about Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia.

Contributions of a hand-held fan to self-management of chronic breathlessness (2017)
Journal Article
Luckett, T., Phillips, J., Johnson, M. J., Farquhar, M., Swan, F., Assen, T., Bhattarai, P., & Booth, S. (2017). Contributions of a hand-held fan to self-management of chronic breathlessness. European respiratory journal, 50(2), Article 1700262. https://doi.org/10.1183/13993003.00262-2017

© ERS 2017. This study explored the benefits of a hand-held fan as perceived by patients with chronic breathlessness and their carers. A secondary multimethod analysis was conducted of interview data collected in three clinical trials. Two researcher... Read More about Contributions of a hand-held fan to self-management of chronic breathlessness.

Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients (2017)
Journal Article
Mather, H., Guo, P., Firth, A., Davies, J. M., Sykes, N., Landon, A., & Murtagh, F. E. (2018). Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients. Palliative medicine, 32(2), 404-412. https://doi.org/10.1177/0269216317727157

© 2017, © The Author(s) 2017. Background: Phase of Illness describes stages of advanced illness according to care needs of the individual, family and suitability of care plan. There is limited evidence on its association with other measures of sympto... Read More about Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients.

Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting (2017)
Journal Article
Digges, M., Hussein, A., Wilcock, A., Crawford, G. B., Boland, J. W., Agar, M. R., Sinnarajah, A., Currow, D. C., & Johnson, M. J. (2018). Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting. Journal of palliative medicine, 21(1), 37-43. https://doi.org/10.1089/jpm.2017.0159

Background Haloperidol is widely prescribed as an anti-emetic in patients receiving palliative care, but there is limited evidence to support and refine its use. Objective To explore the immediate and short-term net clinical effects of haloperidol wh... Read More about Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting.

Towards an understanding of how appraisal of doctors produces its effects: a realist review (2017)
Journal Article
Brennan, N., Bryce, M., Pearson, M., Wong, G., Cooper, C., & Archer, J. (2017). Towards an understanding of how appraisal of doctors produces its effects: a realist review. Medical Education, 51(10), 1002-1013. https://doi.org/10.1111/medu.13348

© 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education Context: Revalidation was launched in the UK to provide assurances to the public that doctors are up to date and fit to practice. Appraisal is a fundamental compone... Read More about Towards an understanding of how appraisal of doctors produces its effects: a realist review.

Care of the dying : a qualitative exploration of foundation year doctors’ experiences (2017)
Journal Article
Redman, M., Pearce, J., Gajebasia, S., Johnson, M., & Finn, G. (2017). Care of the dying : a qualitative exploration of foundation year doctors’ experiences. Medical Education, 51(10), 1025-1036. https://doi.org/10.1111/medu.13358

Context
Foundation Year doctors (FYs), who are newly qualified, are expected to provide care for dying patients. Experiences at this early mandatory stage of training may form the foundation for future encounters, but little is documented about wha... Read More about Care of the dying : a qualitative exploration of foundation year doctors’ experiences.

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol (2017)
Journal Article
Currow, D., Watts, G. J., Johnson, M., McDonald, C. F., Miners, J. O., Somogyi, A. A., Denehy, L., McCaffrey, N., Eckert, D. J., McCloud, P., Louw, S., Lam, L., Greene, A., Fazekas, B., Clark, K. C., Fong, K., Agar, M. R., Joshi, R., Kilbreath, S., Ferreira, D., & Ekström, M. (2017). A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol. BMJ open, 7(7), 1-18. https://doi.org/10.1136/bmjopen-2017-018100

© Article author(s). Introduction Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended-release (ER) o... Read More about A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.

Influence of opioids on immune function in patients with cancer pain: from bench to bedside (2017)
Journal Article
Boland, J. W., & Pockley, A. G. (in press). Influence of opioids on immune function in patients with cancer pain: from bench to bedside. British Journal of Pharmacology, 175(14), 2726-2736. https://doi.org/10.1111/bph.13903

In patients with cancer, opioids are principally used for the management of acute surgical and chronic cancer-related pain. However, opioids have many non-analgesic effects, including direct and indirect effects on cancer cells and on anti-tumour imm... Read More about Influence of opioids on immune function in patients with cancer pain: from bench to bedside.

Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review (2017)
Journal Article
Papoutsi, C., Mattick, K., Pearson, M., Brennan, N., Briscoe, S., & Wong, G. (2017). Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review. The journal of antimicrobial chemotherapy, 72(9), 2418-2430. https://doi.org/10.1093/jac/dkx194

Background
Antimicrobial resistance has led to widespread implementation of interventions for appropriate prescribing. However, such interventions are often adopted without an adequate understanding of the challenges facing doctors-in-training as key... Read More about Social and professional influences on antimicrobial prescribing for doctors-in-training: A realist review.

“Go make your face known”: Collaborative working through the lens of personal relationships (2017)
Journal Article
King, N., Bravington, A., Brooks, J., Melvin, J., & Wilde, D. (2017). “Go make your face known”: Collaborative working through the lens of personal relationships. International journal of integrated care, 17(4), Article 3. https://doi.org/10.5334/ijic.2574

© 2017 The Author(s). Background: Collaborative working between professionals is a key component of integrated care. The academic literature on it largely focuses either on integration between health and social care or on the dynamics of power and id... Read More about “Go make your face known”: Collaborative working through the lens of personal relationships.