All Outputs (4)

Current Insights into Cellular Senescence and Myotoxicity Induced by Doxorubicin: The Role of Exercise and Growth Factors (2022)
Journal Article
Andreou, C., & Matsakas, A. (2022). Current Insights into Cellular Senescence and Myotoxicity Induced by Doxorubicin: The Role of Exercise and Growth Factors. International journal of sports medicine, 43(13), 1084-1096. https://doi.org/10.1055/a-1797-7622

Doxorubicin is an anti-neoplasmic drug that prevents DNA replication but induces senescence and cellular toxicity. Intensive research has focused on strategies to alleviate the doxorubicin-induced skeletal myotoxicity. The aim of the present review i... Read More about Current Insights into Cellular Senescence and Myotoxicity Induced by Doxorubicin: The Role of Exercise and Growth Factors.

Evaluating trastuzumab in the treatment of HER2 positive breast cancer (2020)
Journal Article
Jaques, R., Xu, S., & Matsakas, A. (2020). Evaluating trastuzumab in the treatment of HER2 positive breast cancer. Histology and Histopathology, 35(10), 1059-1075. https://doi.org/10.14670/HH-18-221

© 2020, Histology and Histopathology. All rights reserved. The transmembrane oncoprotein HER2 is encoded by ERBB2 gene and overexpressed in around 20% of invasive breast cancers. It can be specifically targeted by Trastuzumab (Herceptin®), a humanise... Read More about Evaluating trastuzumab in the treatment of HER2 positive breast cancer.

Current Insights into the Potential Misuse of Platelet-based Applications for Doping in Sports (2019)
Journal Article
Scully, D., & Matsakas, A. (2019). Current Insights into the Potential Misuse of Platelet-based Applications for Doping in Sports. International journal of sports medicine, 40(7), 427-433. https://doi.org/10.1055/a-0884-0734

Platelet-based applications are currently used for the delivery of growth factors and other biomolecules as autologous biomaterials in regenerative medicine and cosmetic therapies. Many studies have revealed that platelet-based applications such as p... Read More about Current Insights into the Potential Misuse of Platelet-based Applications for Doping in Sports.

Duchenne muscular dystrophy: genome editing gives new hope for treatment (2018)
Journal Article
Crispi, V., & Matsakas, A. (2018). Duchenne muscular dystrophy: genome editing gives new hope for treatment. Postgraduate Medical Journal, 94(1111), 296-304. https://doi.org/10.1136/postgradmedj-2017-135377

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. Duchenne muscular dystrophy (DMD) is a progressive wasting dis... Read More about Duchenne muscular dystrophy: genome editing gives new hope for treatment.