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All Outputs (6)

Development of a dual flow microfluidic device for the study of barrier systems (2020)
Thesis
Baldwin, L. (2020). Development of a dual flow microfluidic device for the study of barrier systems. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223404

Inflammatory Bowel Diseases (IBD) including Crohn’s Disease and Ulcerative Colitis are chronic conditions characterised by inflammation of the wall of the gastrointestinal tract. IBD has also been shown to have systemic impacts including on the centr... Read More about Development of a dual flow microfluidic device for the study of barrier systems.

Targeted activation of dendritic cells via the CD40 receptor (2018)
Thesis
Wingham, B. (2018). Targeted activation of dendritic cells via the CD40 receptor. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224089

Dendritic cell (DC) activation underpins the patient immune response in multiple cancers, including ovarian cancer. While DCs are detected within the margins of ovarian tumours, DC populations are maintained in an immature state, displaying low level... Read More about Targeted activation of dendritic cells via the CD40 receptor.

Development and integration of simplified real-world to chip interfaces for use in the detection of infectious diseases (2014)
Thesis
Birch, C. (2014). Development and integration of simplified real-world to chip interfaces for use in the detection of infectious diseases. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4216252

Bacterial-based infectious disease, such as sexually transmitted infections and hospital-acquired infections, present a worldwide burden on healthcare issues. To control the spread of infection and to inform clinical treatment, rapid point of care (P... Read More about Development and integration of simplified real-world to chip interfaces for use in the detection of infectious diseases.

Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications (2012)
Thesis
Lumley, E. K. (2012). Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219891

Cancer cells are derived from cells that are termed, and recognised as being 'self', meaning that the immune system does not target them. Many treatments target the tumour through its requirement for large quantities of nutrients. However, this cause... Read More about Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications.

Integrated DNA extraction and amplification on a microfluidic device (2009)
Thesis
Shaw, K. J. (. J. (2009). Integrated DNA extraction and amplification on a microfluidic device. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4209278

An evaluation of DNA extraction and amplification performed in microfluidic systems was carried out, with the aim of integrating the two processes in a single microfluidic device. This integrated device will then be incorporated upstream of capillary... Read More about Integrated DNA extraction and amplification on a microfluidic device.

Streptavidin-cytokine fusion proteins for use as adjuvants in cancer vaccines (2008)
Thesis
Henderson, R. (2008). Streptavidin-cytokine fusion proteins for use as adjuvants in cancer vaccines. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4208726

The work presented in this thesis describes the production and characterisation of recombinant streptavidin-cytokine fusion proteins. Immunoadjuvants can augment the weak or non-existent antitumour response of a patient with cancer to immunotherapy.... Read More about Streptavidin-cytokine fusion proteins for use as adjuvants in cancer vaccines.