All Outputs (31)

Immunomodulation within the head and neck tumour microenvironment (2014)
Thesis
Murray, P. F. (2014). Immunomodulation within the head and neck tumour microenvironment. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4216127

Changes in the immune response have been implicated in the progression of squamous cell carcinoma of the head and neck (HNSCC). Evidence is emerging that processes within the tumour microenvironment can lead to immune modulation and subsequent tumour... Read More about Immunomodulation within the head and neck tumour microenvironment.

Assessing the effects of radiotherapy on head and neck squamous cell carcinoma using microfluidic techniques (2013)
Thesis
Carr, S. D. (2013). Assessing the effects of radiotherapy on head and neck squamous cell carcinoma using microfluidic techniques. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4215491

Objective
The aim of this study was to investigate how HNSCC tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device, respond to radiation treatment.

Materials and Methods
35 patients with HNSCC were recru... Read More about Assessing the effects of radiotherapy on head and neck squamous cell carcinoma using microfluidic techniques.

Expression of angiogenic growth factors in laryngeal carcinoma (2012)
Thesis
Korampalli, T. S. (2012). Expression of angiogenic growth factors in laryngeal carcinoma. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214765

Head and Neck cancer is the sixth most common malignancy in the world and each year over 2,200 cases of carcinoma of the larynx are diagnosed in the UK. Patients have an overall five-year survival rate of 67%. Despite advances in treatment, patient p... Read More about Expression of angiogenic growth factors in laryngeal carcinoma.

Development of micro fluidic based devices for studying tumour biology and evaluating treatment response in head and neck cancer biopsies (2011)
Thesis
Sylvester, D. C. (2011). Development of micro fluidic based devices for studying tumour biology and evaluating treatment response in head and neck cancer biopsies. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214515

Head and Neck Squamous Cell Carcinoma (HNSCC) presents particular challenges to both the researcher and the clinician. Encompassing a group of tumours with distinct epidemiological and oncological behaviour, each sub site differs greatly in its manag... Read More about Development of micro fluidic based devices for studying tumour biology and evaluating treatment response in head and neck cancer biopsies.

Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis (2011)
Thesis
Echrish, H. H. J. (2011). Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4212008

Pancreatic (PC) is the eleventh most common malignancy in the UK but it has the poorest prognosis of all human adenocarcinoma. The autopsy, epidemiological and clinical studies have consistently identified PC as one of the most highly angiogenic and... Read More about Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis.

CXCR4 chemokine receptor antagonists : new metallodrugs (2009)
Thesis
Khan, A. (2009). CXCR4 chemokine receptor antagonists : new metallodrugs. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4216132

Chemokine receptors are a target of growing interest for new therapeutic drugs, as their role in multiple disease states has been demonstrated. The CXCR4/ CXCL12 pairing has been implicated in HIV and cancer, as well as chronic inflammatory diseases,... Read More about CXCR4 chemokine receptor antagonists : new metallodrugs.

Regulatory T cells and circulating cytokines : novel prognostic markers in squamous cells carcinoma of the head & neck (2009)
Thesis
Al Hamarneh, O. (2009). Regulatory T cells and circulating cytokines : novel prognostic markers in squamous cells carcinoma of the head & neck. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4213579

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of cancer worldwide and is considered a highly immunosuppressive tumour. Advances in the treatment modalities for HNSCC over the last 20 years involving surgery, radiotherapy... Read More about Regulatory T cells and circulating cytokines : novel prognostic markers in squamous cells carcinoma of the head & neck.

Identification of MRSA-specific peptides and expression of peptide containing recombinant proteins for targeted photodynamic therapy (2009)
Thesis
Vince, R. V. (2009). Identification of MRSA-specific peptides and expression of peptide containing recombinant proteins for targeted photodynamic therapy. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4209328

Staphylococcus aureus (S. aureus) is an opportunistic pathogen capable of causing infection at multiple sites and is one of the predominant organisms found in chronic wounds, such as venous ulcers. Furthermore, there is an ever-increasing prevalence... Read More about Identification of MRSA-specific peptides and expression of peptide containing recombinant proteins for targeted photodynamic therapy.

Streptavidin-cytokine fusion proteins for use as adjuvants in cancer vaccines (2008)
Thesis
Henderson, R. (2008). Streptavidin-cytokine fusion proteins for use as adjuvants in cancer vaccines. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4208726

The work presented in this thesis describes the production and characterisation of recombinant streptavidin-cytokine fusion proteins. Immunoadjuvants can augment the weak or non-existent antitumour response of a patient with cancer to immunotherapy.... Read More about Streptavidin-cytokine fusion proteins for use as adjuvants in cancer vaccines.

The role of chromosome 22 in the progression of head and neck squamous cell carninoma (2003)
Thesis
Condon, L. T. (2003). The role of chromosome 22 in the progression of head and neck squamous cell carninoma. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223891

Head and neck squamous cell carcinoma (HNSCC) is one o f the ten most frequent cancers in the world. Despite advances in surgery, radiotherapy and chemotherapy over the last 30 years, there has been little improvement in the mortality rate from this... Read More about The role of chromosome 22 in the progression of head and neck squamous cell carninoma.

Genetic analysis of squamous cell carcinoma of the head and neck (2002)
Thesis
Ashman, J. N. E. (2002). Genetic analysis of squamous cell carcinoma of the head and neck. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214191

Head and neck squamous cell carcinoma (HNSCC) is the sixth commonest cancer worldwide with an increasing incidence in developing countries. Despite numerous advances in surgery, radiotherapy and chemotherapy over the past few decades the overall surv... Read More about Genetic analysis of squamous cell carcinoma of the head and neck.