All Outputs (4)

The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation (2020)
Thesis
Stinson, R. J. (2020). The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222863

Human Rhinovirus (hRV) is a major cause of upper respiratory tract infections (URTIs) and is linked to lower respiratory tract infections (LRTIs) and airway diseases exacerbations. Cough, airway inflammation and hypersensation are common symptoms of... Read More about The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation.

The effect of human rhinovirus-16 on thermo-TRP channels, hypotonic activation and ATP release (2019)
Thesis
Atkinson, S. K. (2019). The effect of human rhinovirus-16 on thermo-TRP channels, hypotonic activation and ATP release. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4221658

Human rhinovirus (RV-16) infections are major cause of upper respiratory tract infections (URTI) and are associated with acute exacerbations of asthma and COPD. URTIs are associated with excessive production of mucus within the airway, particularly i... Read More about The effect of human rhinovirus-16 on thermo-TRP channels, hypotonic activation and ATP release.

The modulation of Transient Receptor Potential A1 channel by natural and novel semi-synthetic compounds via non-covalent modification (2016)
Thesis
Knaggs, J. D. (2016). The modulation of Transient Receptor Potential A1 channel by natural and novel semi-synthetic compounds via non-covalent modification. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219218

Transient Receptor Potential A1 (TRPA1) is commonly known as the detector of a broad range of noxious chemical agents both exogenous and endogenous. TRPA1 detects these chemicals through a reversible covalent modification mechanism that allows most e... Read More about The modulation of Transient Receptor Potential A1 channel by natural and novel semi-synthetic compounds via non-covalent modification.

The effects of hydrogen sulfide on HEK-293 cells and human primary bronchial fibroblasts (2015)
Thesis
Kaura, V. (2015). The effects of hydrogen sulfide on HEK-293 cells and human primary bronchial fibroblasts. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218567

Hydrogen sulfide (H2S) is a key biologically relevant signalling molecule and has been recognised as the third endogenous gasotransmitter. H2S modulates various biological functions through complex mechanisms which may involve Transient Receptor Pote... Read More about The effects of hydrogen sulfide on HEK-293 cells and human primary bronchial fibroblasts.