All Outputs (8)

Investigation and characterization of MP derived from media conditioned by various cancer cell lines and their effect on human umbilical vein endothelial cells (HUVECs) under static and flow conditions (2020)
Thesis
Algarni, A. E. S. (2020). Investigation and characterization of MP derived from media conditioned by various cancer cell lines and their effect on human umbilical vein endothelial cells (HUVECs) under static and flow conditions. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4222898

Microparticles (MP) are procoagulant due to tissue factor and phospholipid exposure on the surface. MP are tumour-derived and can be a beneficial biomarker of cancer to recognize individuals who are susceptible to venous thrombosis. The aim of the pr... Read More about Investigation and characterization of MP derived from media conditioned by various cancer cell lines and their effect on human umbilical vein endothelial cells (HUVECs) under static and flow conditions.

Bioimprinting technologies for removal of myeloblasts from peripheral blood (2018)
Thesis
Medlock, J. (2018). Bioimprinting technologies for removal of myeloblasts from peripheral blood. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223476

Acute Myeloid Leukaemia (AML) is a malignancy occurring in the bone marrow and blood whereby immature and defective blast cells are overproduced. As a genetic condition, no cure is available. The condition is traditionally managed by treatment relian... Read More about Bioimprinting technologies for removal of myeloblasts from peripheral blood.

Novel interventional therapies to improve cardiovascular risk in women with polycystic ovary syndrome (2018)
Thesis
Javed, Z. (2018). Novel interventional therapies to improve cardiovascular risk in women with polycystic ovary syndrome. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4220685

Introduction:
Polycystic ovary syndrome (PCOS) is associated with a diverse range of endocrine, metabolic and cardiovascular risk factors. Low vitamin D in PCOS is associated with multiple cardiovascular risk factors and vitamin D replacement therap... Read More about Novel interventional therapies to improve cardiovascular risk in women with polycystic ovary syndrome.

Characterisation of duramycin as an anti-cancer agent (2016)
Thesis
Broughton, L. J. (2016). Characterisation of duramycin as an anti-cancer agent. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219417

Duramycin is a relatively small (~2kDa) tetracyclic peptide that has a defined three-dimensional (3D) structure, this structure forms a stable binding pocket which specifically recognises the plasma membrane phospholipid phosphatidylethanolamine (PE)... Read More about Characterisation of duramycin as an anti-cancer agent.

Exercise prehabilitation in colorectal cancer surgery patients : the effects on physical functioning, health related quality of life and markers of cellular protection (2016)
Thesis
Northgraves, M. J. (2016). Exercise prehabilitation in colorectal cancer surgery patients : the effects on physical functioning, health related quality of life and markers of cellular protection. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219478

Since being introduced in the late 1990’s, enhancing recovery after surgery (ERAS) protocols have been promoted for inclusion in the care pathway for colorectal cancer patients scheduled for resection surgery (Gustaffson et al., 2012). This multimoda... Read More about Exercise prehabilitation in colorectal cancer surgery patients : the effects on physical functioning, health related quality of life and markers of cellular protection.

Study of the thrombogenicity induced by the cytotoxic treatment of malignant disease (2014)
Thesis
Hall, J. (2014). Study of the thrombogenicity induced by the cytotoxic treatment of malignant disease. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4216550

Cancer and its treatment are frequently complicated by the development of venous thromboembolism (VTE). Interestingly, VTE incidence rates vary according to tumour type and the chemotherapy regimen administered. Yet, the precise mechanisms responsibl... Read More about Study of the thrombogenicity induced by the cytotoxic treatment of malignant disease.

Endothelial function response to different modes of acute and chronic exercise in both health and diseased populations (2014)
Thesis
Kirk, R. J. T. (2014). Endothelial function response to different modes of acute and chronic exercise in both health and diseased populations. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220509

Endothelial microparticles (EMP) offer an insight into the state of the endothelium and are known to be elevated in diseases characterised by endothelial dysfunction (ED) (Horstman et al., 2004; Vince et al., 2009a). EMP have also been shown to incre... Read More about Endothelial function response to different modes of acute and chronic exercise in both health and diseased populations.

Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis (2011)
Thesis
Echrish, H. H. J. (2011). Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4212008

Pancreatic (PC) is the eleventh most common malignancy in the UK but it has the poorest prognosis of all human adenocarcinoma. The autopsy, epidemiological and clinical studies have consistently identified PC as one of the most highly angiogenic and... Read More about Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis.