All Outputs (3)

Investigating the importance of CBX2’s structural motifs for its chromatin interactions and pro-oncogenic epigenetic regulatory function in triple negative breast cancer (2022)
Thesis
Dobrowinski, W. (2022). Investigating the importance of CBX2’s structural motifs for its chromatin interactions and pro-oncogenic epigenetic regulatory function in triple negative breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4291232

Epigenetics is the study of the change in gene expression patterns that are not caused by direct alterations in the DNA nucleotide sequence but instead are as a result of the dynamic remodelling of the chromatin state. Regulation of the chromatin lan... Read More about Investigating the importance of CBX2’s structural motifs for its chromatin interactions and pro-oncogenic epigenetic regulatory function in triple negative breast cancer.

Investigating the role Of CBX2 to promote cell growth in triple negative breast cancer (2022)
Thesis
Bilton, L. (2022). Investigating the role Of CBX2 to promote cell growth in triple negative breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4240594

Breast cancer is the uncontrolled proliferation of breast cells and is one of the most common cancers in the UK. It is a complex disease that can be divided into different subtypes based upon the presence or lack of hormone receptors, namely the oest... Read More about Investigating the role Of CBX2 to promote cell growth in triple negative breast cancer.

Establishing a flow-based system for repressing target gene expression in a microfluidic device using a glioblastoma spheroid model (2022)
Thesis
Hosni Ep Ben Daoud, I. (2022). Establishing a flow-based system for repressing target gene expression in a microfluidic device using a glioblastoma spheroid model. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224543

Glioblastoma (GBM) is a deadly disease with poor prognosis. The gold standard treatment is surgery followed by chemoradiotherapy almost always including Temozolomide. Despite extensive research for new therapeutic approaches relapse after treatment s... Read More about Establishing a flow-based system for repressing target gene expression in a microfluidic device using a glioblastoma spheroid model.