All Outputs (3)

CXCR4 chemokine receptor antagonists : new metallodrugs (2009)
Thesis
Khan, A. (2009). CXCR4 chemokine receptor antagonists : new metallodrugs. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4216132

Chemokine receptors are a target of growing interest for new therapeutic drugs, as their role in multiple disease states has been demonstrated. The CXCR4/ CXCL12 pairing has been implicated in HIV and cancer, as well as chronic inflammatory diseases,... Read More about CXCR4 chemokine receptor antagonists : new metallodrugs.

Configurationally restricted bis-tetraazamacrocyclic complexes: chemokine receptor antagonists (2009)
Thesis
McRobbie, G. W. J. (2009). Configurationally restricted bis-tetraazamacrocyclic complexes: chemokine receptor antagonists. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4213191

The chemokine receptor CXCR4 is a trans-membrane protein which has been implicated in many physiological and pathological processes including cancer, rheumatoid arthritis and most significantly HIV replication. CXCR4 plays a vital role in embryonic d... Read More about Configurationally restricted bis-tetraazamacrocyclic complexes: chemokine receptor antagonists.

Synthesis of tetraazamacrocyclic complexes: Biomedical applications (2009)
Thesis
Mewis, R. E. (2009). Synthesis of tetraazamacrocyclic complexes: Biomedical applications. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4208988

Tetraazamacrocyclic frameworks of 1,4,7,10-tetraazacylcododecane (cyclen) and 1,4,8,11-tetraazacyclotetradecane (cyclam) with functional pendent arms and porphyrins with solubilising polyethylene glycol (PEG) chains have been synthesised. The pendent... Read More about Synthesis of tetraazamacrocyclic complexes: Biomedical applications.