All Outputs (3)

An investigation into the effect of oxLDL and cyclic nucleotides on platelet cytoskeletal function (2020)
Thesis
Ahmed, Y. (2020). An investigation into the effect of oxLDL and cyclic nucleotides on platelet cytoskeletal function. (Thesis). Hull York Medical School, The University of Hull and The University of York. Retrieved from https://hull-repository.worktribe.com/output/4200904

Atherosclerosis is a major underlying cause in cardiovascular disease and a significant health concern in developed countries. Part of the mechanism by which platelets are linked to this process is via their activation by oxidised Low-Density Lipopro... Read More about An investigation into the effect of oxLDL and cyclic nucleotides on platelet cytoskeletal function.

Association of type 1 inositol 1,4,5-trisphosphate receptor (IP₃R1) with protein kinase A and A-kinase Anchoring Protein 9 (AKAP9) in platelets (2017)
Thesis
Trivedi, A. N. (2017). Association of type 1 inositol 1,4,5-trisphosphate receptor (IP₃R1) with protein kinase A and A-kinase Anchoring Protein 9 (AKAP9) in platelets. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219204

Cyclic adenosine monophsphoate (cAMP) signalling is thought to regulate inositol-1,4,5 trisphosphate (IP₃)-mediated calcium (Ca²⁺) mobilisation in platelets through protein kinase A (PKA)-mediated phosphorylation, leading to inhibition of inositol-1,... Read More about Association of type 1 inositol 1,4,5-trisphosphate receptor (IP₃R1) with protein kinase A and A-kinase Anchoring Protein 9 (AKAP9) in platelets.

cAMP signaling reverses platelet spreading via inhibition of RhoA (2016)
Thesis
Yusuf, M. Z. (2016). cAMP signaling reverses platelet spreading via inhibition of RhoA. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218863

Prostacyclin (PGI₂) is a key regulator of platelet function. There is a significant field of research which outlines the role of PGI₂ in inhibiting platelets in circulation, and therefore playing a major role in the prevention of excessive thrombus f... Read More about cAMP signaling reverses platelet spreading via inhibition of RhoA.