Skip to main content

Research Repository

Advanced Search

All Outputs (3)

Investigating the importance of CBX2’s structural motifs for its chromatin interactions and pro-oncogenic epigenetic regulatory function in triple negative breast cancer (2022)
Thesis
Dobrowinski, W. (2022). Investigating the importance of CBX2’s structural motifs for its chromatin interactions and pro-oncogenic epigenetic regulatory function in triple negative breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4291232

Epigenetics is the study of the change in gene expression patterns that are not caused by direct alterations in the DNA nucleotide sequence but instead are as a result of the dynamic remodelling of the chromatin state. Regulation of the chromatin lan... Read More about Investigating the importance of CBX2’s structural motifs for its chromatin interactions and pro-oncogenic epigenetic regulatory function in triple negative breast cancer.

Establishing a novel 3-dimensional microfluidic model of bunyavirus Infection to characterise exosome release from tumour cells (2022)
Thesis
Marsh, D. (2022). Establishing a novel 3-dimensional microfluidic model of bunyavirus Infection to characterise exosome release from tumour cells. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224638

The order Bunyavirales represents the largest and most diverse taxonomic grouping of negative-sense RNA viruses, some of which are associated with significant diseases in humans and livestock. The global emergence of these viruses is exacerbated by t... Read More about Establishing a novel 3-dimensional microfluidic model of bunyavirus Infection to characterise exosome release from tumour cells.

Investigating the role of CBX2 in ER- positive breast cancer (2019)
Thesis
Waters, E. J. (2019). Investigating the role of CBX2 in ER- positive breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4222704

Breast cancer is the most common form of cancer in women, with oestrogen receptor (ER) positive breast cancers being the most common subtype. Although there are targeted endocrine therapies for this receptor, resistance mechanisms mean that they are... Read More about Investigating the role of CBX2 in ER- positive breast cancer.