All Outputs (4)

Characterisation of targeted imaging and theranostic agents for cancer and fibrosis (2018)
Thesis
Thompson, J. A. (2018). Characterisation of targeted imaging and theranostic agents for cancer and fibrosis. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4221539

Positron emission tomography (PET) imaging is a non-invasive modality that permits the characterisation of biological processes at the molecular level. Integrin αvβ6 and the chemokine receptor CXCR4 are important receptors in the pathogenesis of vari... Read More about Characterisation of targeted imaging and theranostic agents for cancer and fibrosis.

Development and evaluation of CXCR4 receptor targeted probes for medical imaging applications (2017)
Thesis
Lee, R. E. (2017). Development and evaluation of CXCR4 receptor targeted probes for medical imaging applications. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224548

The chemokine receptor CXCR4 has been shown to be overexpressed in over 23 different types of cancers, making it an attractive target for therapeutic and imaging agents. Molecular imaging techniques, such as positron emission tomography (PET) and sin... Read More about Development and evaluation of CXCR4 receptor targeted probes for medical imaging applications.

Probing cardiac metabolism in uraemic cardiomyopathy (2017)
Thesis
Atkinson, R. (2017). Probing cardiac metabolism in uraemic cardiomyopathy. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220698

Cardiovascular complications are the leading cause of death in patients with chronic kidney disease (CKD). Uraemic cardiomyopathy (UCM) is characterised by structural and cellular remodelling including left ventricular hypertrophy (LVH), metabolic re... Read More about Probing cardiac metabolism in uraemic cardiomyopathy.

The development of nuclear receptor imaging agents (2014)
Thesis
Allott, L. (2014). The development of nuclear receptor imaging agents. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4217221

Positron emission tomography (PET) is a molecular imaging technique which allows visualisation and quantification of biomarkers by administering a positron-emitting molecular probe. The steroid hormone receptors for estrogen and progesterone are over... Read More about The development of nuclear receptor imaging agents.