All Outputs (17)

An Exploration of Factors Affecting Timely Referral of Patients with Chronic Limb-Threatening Ischaemia (2025)
Thesis
Atkins, E. (2025). An Exploration of Factors Affecting Timely Referral of Patients with Chronic Limb-Threatening Ischaemia [Doctoral thesis, Hull York Medical School]. https://hull-repository.worktribe.com/output/5130250

Chronic limb-threatening ischaemia (CLTI) is the end-stage of peripheral arterial disease. It is associated with significant risks of limb loss and mortality, which increase with delays to revascularisation. There is currently little understanding of... Read More about An Exploration of Factors Affecting Timely Referral of Patients with Chronic Limb-Threatening Ischaemia.

Addressing delays to treatment in patients with chronic limb-threatening ischaemia (2023)
Thesis
Birmpili, P. (2023). Addressing delays to treatment in patients with chronic limb-threatening ischaemia [Doctoral thesis, Hull York Medical School]. https://hull-repository.worktribe.com/output/4371299

Patients with CLTI often face long delays from referral to the vascular surgery service and hospital admission to revascularisation, and there is limited evidence on the effect of these delays on patient outcomes. This thesis aims to identify factors... Read More about Addressing delays to treatment in patients with chronic limb-threatening ischaemia.

Mechanochemical ablation in the treatment of superficial venous incompetence (2021)
Thesis
Mohamed, A. (2021). Mechanochemical ablation in the treatment of superficial venous incompetence [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4223528

Background
The routine management of venous incompetence has undergone considerable changes in the last two decades led by the introduction of minimally invasive endovenous techniques. At the heart of these changes has been a drive to offer patients... Read More about Mechanochemical ablation in the treatment of superficial venous incompetence.

Alternative exercise programmes for the treatment of intermittent claudication - from unsupervised home-based walking to supervised high-intensity interval cycling (2021)
Thesis
Pymer, S. (2021). Alternative exercise programmes for the treatment of intermittent claudication - from unsupervised home-based walking to supervised high-intensity interval cycling [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4223166

Supervised exercise programmes (SEP) for intermittent claudication (IC) suffer from low provision and uptake rates. As such, alternative interventions should be explored, such as home-based exercise programmes (HEP) and high-intensity interval traini... Read More about Alternative exercise programmes for the treatment of intermittent claudication - from unsupervised home-based walking to supervised high-intensity interval cycling.

Investigating the effectiveness of dialkylcarbamoylchloride-coated wound dressings in the prevention of surgical site infection (2019)
Thesis
Totty, J. P. (2019). Investigating the effectiveness of dialkylcarbamoylchloride-coated wound dressings in the prevention of surgical site infection [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4222026

Background: Surgical site infection (SSI) is the second most common healthcare acquired infection and may complicate between 5 and 30% of all surgical procedures. Avoidance of antibiotic or antimicrobial agents is important to future prevention strat... Read More about Investigating the effectiveness of dialkylcarbamoylchloride-coated wound dressings in the prevention of surgical site infection.

Optimising Outcomes in the Management of Superficial Venous Insufficiency (2018)
Thesis
Nandhra, S. (2018). Optimising Outcomes in the Management of Superficial Venous Insufficiency [Doctoral thesis, Hull York Medical School]. https://hull-repository.worktribe.com/output/5430042

Introduction
Superficial venous insufficiency (SVI) of the lower limb is a common condition with significant quality of life (QoL) impairment. Endovenous thermal ablative (EVTA) treatments have been shown to offer superiority over conventional open... Read More about Optimising Outcomes in the Management of Superficial Venous Insufficiency.

Surgical site infection following major lower limb amputation : analysing the clinical effectiveness of antibiotic prophylaxis duration and skin preparation (2017)
Thesis
Souroullas, P. (2017). Surgical site infection following major lower limb amputation : analysing the clinical effectiveness of antibiotic prophylaxis duration and skin preparation [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4221143

Background: Major LLA remains a common operation in the United Kingdom with ⁓5000 procedures performed yearly. Amputations are described as ‘clean surgery’ and SSIs in this patient cohort have been previously under-reported. The true incidence lies b... Read More about Surgical site infection following major lower limb amputation : analysing the clinical effectiveness of antibiotic prophylaxis duration and skin preparation.

The role of peroneal nerve electrical neuromuscular stimulation in the augmentation of lower limb circulatory physiology in lower limb arterial and venous disease (2015)
Thesis
Barnes, R. M. D. (2015). The role of peroneal nerve electrical neuromuscular stimulation in the augmentation of lower limb circulatory physiology in lower limb arterial and venous disease [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4218711

Introduction:
Studies in healthy volunteers have demonstrated that peroneal nerve stimulation augments blood flow. The studies described within this thesis aimed to establish whether use of the geko™ neuromuscular stimulation device was effective a... Read More about The role of peroneal nerve electrical neuromuscular stimulation in the augmentation of lower limb circulatory physiology in lower limb arterial and venous disease.

Preoperative supervised exercise and outcomes following elective abdominal aortic aneurysm repair (2014)
Thesis
Barakat, H. M. (2014). Preoperative supervised exercise and outcomes following elective abdominal aortic aneurysm repair [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4216676

Objective
The aim of this research was to evaluate the role of preoperative supervised exercise training on perioperative outcomes and cardiopulmonary exercise testing (CPET) parameters in patients undergoing elective abdominal aortic aneurysm (AAA)... Read More about Preoperative supervised exercise and outcomes following elective abdominal aortic aneurysm repair.

The validity, reliability and responsiveness of procedure based assessment in simulated vascular procedures (2014)
Thesis
Green, L. A. (2014). The validity, reliability and responsiveness of procedure based assessment in simulated vascular procedures [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4216921

Introduction

Procedure based assessment (PBA) has been shown to be valid and reliable in the workplace however whether this translates to the simulation setting has not yet been demonstrated. Therefore the aim of this thesis is to demonstrate that... Read More about The validity, reliability and responsiveness of procedure based assessment in simulated vascular procedures.

Optimising outcomes in the treatment of superficial venous insufficiency (2014)
Thesis
Wallace, T. M. (2014). Optimising outcomes in the treatment of superficial venous insufficiency [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4216422

The traditional “gold-standard” treatment for symptomatic SVI affecting the GSV is conventional open surgery and stripping under general anaesthesia. Despite improved QoL and cost-effectiveness when compared to conservative management, conventional s... Read More about Optimising outcomes in the treatment of superficial venous insufficiency.

An RCT of clinical and cost effectiveness of endovenous laser therapy in the treatment of varicose veins secondary to isolated saphenopopliteal incompetence and small saphenous reflux (2014)
Thesis
Samuel, N. (2014). An RCT of clinical and cost effectiveness of endovenous laser therapy in the treatment of varicose veins secondary to isolated saphenopopliteal incompetence and small saphenous reflux [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4216284

BACKGROUND
Lower limb varicosities are common and cause significant impairment of quality of life to the sufferers. Patients with small saphenous incompetence form a small but significant part of this group who have traditionally been treated by sur... Read More about An RCT of clinical and cost effectiveness of endovenous laser therapy in the treatment of varicose veins secondary to isolated saphenopopliteal incompetence and small saphenous reflux.

Optimising outcomes in the treatment of lower limb varicose veins (2012)
Thesis
Mekako, A. (2012). Optimising outcomes in the treatment of lower limb varicose veins [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4214091

Varicose veins are dilated and tortuous subcutaneous veins, which affect a significant proportion of adults. They cause physical and emotional symptoms, and affect quality of life in sufferers. The management of varicose veins has evolved since the e... Read More about Optimising outcomes in the treatment of lower limb varicose veins.

Molecular imaging of gene transduction in cardiac transplantation (2012)
Thesis
Rao, V. P. (2012). Molecular imaging of gene transduction in cardiac transplantation [Doctoral thesis, University of Hull]. https://hull-repository.worktribe.com/output/4214665

This thesis is based on a series of experiments aimed at designing a model of gene transfer to the transplanted heart. The use of viral vector-based gene therapy to target pathological processes following cardiac transplantation faces many challenges... Read More about Molecular imaging of gene transduction in cardiac transplantation.

Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress (2011)
Thesis
Heng, M. S. T. (2011). Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress [Doctoral thesis, University of Hull]. https://hull-repository.worktribe.com/output/4213506

Abdominal aortic aneurysms (AAAs) cause 5,000 deaths a year in the UK. Self-examination for AAAs may provide an economic and practical solution. Matrix metalloproteinase (MMP) concentration is elevated and levels of their natural inhibitors - Tissue... Read More about Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress.

Minimally invasive treatment of venous insufficiency using endovenous laser ablation (2011)
Thesis
Carradice, D. (2011). Minimally invasive treatment of venous insufficiency using endovenous laser ablation [Doctoral thesis, Hull York Medical School, the University of Hull and the University of York]. https://hull-repository.worktribe.com/output/4211989

Background

Venous insufficiency is very common and causes significant quality of life (QoL) impairment. Conventional open surgery featuring junction ligation, stripping of the axial vein and phlebectomy is known to offer significant benefits over... Read More about Minimally invasive treatment of venous insufficiency using endovenous laser ablation.

Plasma tissue factor, tissue factor pathway inhibitor and restenosis following femoropopliteal percutaneous transluminal angioplasty in claudicants (2011)
Thesis
Ray, B. (2011). Plasma tissue factor, tissue factor pathway inhibitor and restenosis following femoropopliteal percutaneous transluminal angioplasty in claudicants [Doctoral thesis, University of Hull]. https://hull-repository.worktribe.com/output/4211926

Introduction: The primary goal in the management of intermittent claudication is to decrease cardiovascular morbidity and mortality by disease modifying therapy. However percutaneous transluminal angioplasty (PTA) is often performed to improve limb r... Read More about Plasma tissue factor, tissue factor pathway inhibitor and restenosis following femoropopliteal percutaneous transluminal angioplasty in claudicants.