All Outputs (2)

Adrenomedullin and tumour angiogenesis (2005)
Journal Article
Nikitenko, L. L., Fox, S. B., Kehoe, S., Rees, M. C., & Bicknell, R. (2006). Adrenomedullin and tumour angiogenesis. The British Journal of Cancer, 94(1), 1-7. https://doi.org/10.1038/sj.bjc.6602832

The angiogenic activity of peptide adrenomedullin (AM) was first shown in 1998 . Since then, a number of reports have confirmed the ability of AM to induce the growth and migration of isolated vascular endothelial and smooth muscle cells in vitro and... Read More about Adrenomedullin and tumour angiogenesis.

Antiangiogenic activity of a domain deletion mutant of tissue plasminogen activator containing kringle 2 (2005)
Journal Article
Carroll, V. A., Nikitenko, L. L., Bicknell, R., & Harris, A. L. (2005). Antiangiogenic activity of a domain deletion mutant of tissue plasminogen activator containing kringle 2. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(4), 736-741. https://doi.org/10.1161/01.ATV.0000157980.15710.2b

Objective - The thrombolytic therapy drug, Reteplase, is a domain deletion mutant of tissue plasminogen activator (tPA), comprising the kringle 2 and protease (K2P) domains. Some kringle domains of hemostatic proteins are antiangiogenic and promote a... Read More about Antiangiogenic activity of a domain deletion mutant of tissue plasminogen activator containing kringle 2.