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Impact of P2RX7 ablation on the morphological, mechanical and tissue properties of bones in a murine model of duchenne muscular dystrophy (2016)
Journal Article
Mohamad, N. S., Sinadinos, A., Górecki, D. C., Zioupos, P., & Tong, J. (2016). Impact of P2RX7 ablation on the morphological, mechanical and tissue properties of bones in a murine model of duchenne muscular dystrophy. Journal of biomechanics, 49(14), 3444-3451. https://doi.org/10.1016/j.jbiomech.2016.09.016

Duchenne muscular dystrophy (DMD) is an inherited, lethal disorder characterised by progressive muscle degeneration and associated bone abnormalities. We have previously demonstrated that P2RX7 purinergic receptors contribute to the pathogenesis of D... Read More about Impact of P2RX7 ablation on the morphological, mechanical and tissue properties of bones in a murine model of duchenne muscular dystrophy.

Towards new material biomarkers for fracture risk (2016)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J. P., Lyburn, I., Martin, R. M., …Zioupos, P. (2016). Towards new material biomarkers for fracture risk. Bone, 93, 55-63. https://doi.org/10.1016/j.bone.2016.09.006

Osteoporosis is a prevalent bone condition, characterised by low bone mass and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone mineral density (BMD) usin... Read More about Towards new material biomarkers for fracture risk.

Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter (2016)
Journal Article
Dicken, A. J., Evans, J. P. O., Rogers, K. D., Stone, N., Greenwood, C., Godber, S. X., …Zioupos, P. (2016). Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter. Scientific reports, 6, Article 29011. https://doi.org/10.1038/srep29011

Osteoporotic fractures present a significant social and economic burden, which is set to rise commensurately with the aging population. Greater understanding of the physicochemical differences between osteoporotic and normal conditions will facilitat... Read More about Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter.