All Outputs (5)

Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach (2016)
Thesis
Cheah, R. (2016). Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218576

Radiotherapy remains the standard treat74ment for head and neck squamous cell carcinoma (HNSCC), however, resistance remains a real clinical problem despite the improvements and development of new treatment strategies. Patient outcome could potential... Read More about Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach.

Role of hypoxia-induced ADAM 10 in colorectal cancer progression (2016)
Thesis
Todd, A. E. (2016). Role of hypoxia-induced ADAM 10 in colorectal cancer progression. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219363

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and is the second deadliest form of cancer within the UK. The majority of CRC arises sporadically, as a result of epigenetic alterations transforming normal epithelium to malignan... Read More about Role of hypoxia-induced ADAM 10 in colorectal cancer progression.

An observational pilot study to assess the potential of a microfluidic tissue culture model to predict rectal cancer response to neo-adjuvant therapy (2016)
Thesis
Patel, R. (2016). An observational pilot study to assess the potential of a microfluidic tissue culture model to predict rectal cancer response to neo-adjuvant therapy. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218991

Radiotherapy has been reported to induce apoptosis and prevent the proliferation of malignant cells. Complete clinical response to neo-adjuvant long course chemoradiotherapy has been identified in up to 30% of patients with locally advanced rectal ca... Read More about An observational pilot study to assess the potential of a microfluidic tissue culture model to predict rectal cancer response to neo-adjuvant therapy.

Investigating the role of WSB-1 in breast cancer (2016)
Thesis
Poujade, F. (2016). Investigating the role of WSB-1 in breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219511

Breast cancer is the second most represented cancer type worldwide and will affect 1 in 8 women in the UK. Overall patient survival can reach 90% when the disease is diagnosed early but rapidly drops as the tumour progresses and metastasises. The ste... Read More about Investigating the role of WSB-1 in breast cancer.

The effect of HNSCC-derived soluble factors on the proliferation and function of immune cells (2016)
Thesis
Smith, J. D. (2016). The effect of HNSCC-derived soluble factors on the proliferation and function of immune cells. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219345

Malignant epithelium and associated stromal cells secrete soluble factors which may influence tumour evasion of host immunity. The effect of these factors on the proliferation and function of individual immune cell populations has been investigated a... Read More about The effect of HNSCC-derived soluble factors on the proliferation and function of immune cells.