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All Outputs (2)

The role of scavenger receptors in oxidised low-density lipoprotein induced platelet hyperactivity (2016)
Thesis
Woodward, C. (2016). The role of scavenger receptors in oxidised low-density lipoprotein induced platelet hyperactivity. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218666

Increased platelet hyperactivity is a common consequence of hyperlipidemia and is associated with increased risk of acute coronary syndromes. Platelet interaction with oxidised low-density lipoprotein (oxLDL) is believed to play a crucial role in pla... Read More about The role of scavenger receptors in oxidised low-density lipoprotein induced platelet hyperactivity.

PDE3A signalling in blood platelets (2016)
Thesis
Law, R. (2016). PDE3A signalling in blood platelets. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218467

Cyclic 3’, 5’ adenosine monophosphate (cAMP) signalling downstream of prostacyclin (PGI₂) is a key inhibitory pathway in blood platelets. This pathway is dynamically regulated by phosphodiesterase 3A (PDE3A), which hydrolyses cAMP into metabolically... Read More about PDE3A signalling in blood platelets.