All Outputs (4)

Development and evaluation of CXCR4 receptor targeted probes for medical imaging applications (2017)
Thesis
Lee, R. E. (2017). Development and evaluation of CXCR4 receptor targeted probes for medical imaging applications. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224548

The chemokine receptor CXCR4 has been shown to be overexpressed in over 23 different types of cancers, making it an attractive target for therapeutic and imaging agents. Molecular imaging techniques, such as positron emission tomography (PET) and sin... Read More about Development and evaluation of CXCR4 receptor targeted probes for medical imaging applications.

A spectroscopic and imaging investigation of sporopollenin-metal interactions (2017)
Thesis
Alkhatib, F. M. (2017). A spectroscopic and imaging investigation of sporopollenin-metal interactions. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220724

The main objective has been the determination of the nature of the interaction of metal complexes and salts with the surface of sporopollenin exine capsules (SEC) and other naturally occurring spore exines. These natural materials derived from plant... Read More about A spectroscopic and imaging investigation of sporopollenin-metal interactions.

Probing cardiac metabolism in uraemic cardiomyopathy (2017)
Thesis
Atkinson, R. (2017). Probing cardiac metabolism in uraemic cardiomyopathy. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220698

Cardiovascular complications are the leading cause of death in patients with chronic kidney disease (CKD). Uraemic cardiomyopathy (UCM) is characterised by structural and cellular remodelling including left ventricular hypertrophy (LVH), metabolic re... Read More about Probing cardiac metabolism in uraemic cardiomyopathy.

Development of optimised MRI contrast agents for copper(I) click reactions (2017)
Thesis
Aloraibi, F. K. M. (2017). Development of optimised MRI contrast agents for copper(I) click reactions. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224113

This research has been focused on synthesising three gadolinium(III) 1,4,7-triacetic acid-1,4,7,10-tetraazacyclododecane (DO3A) macrocyclic complexes (Gd6, Gd7, Gd8) as potential T1 MRI contrast agents. Alkyne derivativised chelators were synthesised... Read More about Development of optimised MRI contrast agents for copper(I) click reactions.