All Outputs (867)

The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance (2023)
Journal Article
Mahmoudi-Aznaveh, A., Tavoosidana, G., Najmabadi, H., Azizi, Z., & Ardestani, A. (2023). The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance. Frontiers in endocrinology, 14, Article 1303930. https://doi.org/10.3389/fendo.2023.1303930

Introduction: An insufficient functional beta cell mass is a core pathological hallmark of type 2 diabetes (T2D). Despite the availability of several effective pharmaceuticals for diabetes management, there is an urgent need for novel medications to... Read More about The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance.

From textile waste to carbon nanomaterials for offshore wind turbine blades (2023)
Thesis
Marsden, H. (2023). From textile waste to carbon nanomaterials for offshore wind turbine blades. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4459343

The aim of this research was to determine the feasibility of carbon production from the pyrolysis of textile waste, seeking a way of increasing the sustainability of “fast fashion” and recycling the 92 million tonnes of textile waste entering landfil... Read More about From textile waste to carbon nanomaterials for offshore wind turbine blades.

Women’s football subculture of misogyny: the escalation to online gender-based violence (2023)
Journal Article
Fenton, A., Ahmed, W., Hardey, M., Boardman, R., & Kavanagh, E. (in press). Women’s football subculture of misogyny: the escalation to online gender-based violence. European Sport Management Quarterly, https://doi.org/10.1080/16184742.2023.2270566

Research question Given the worldwide growth of women’s football and its presence on social media, it is essential to explore and understand fan attitudes and culture. Research methods This article provides the first empirical social media netnogr... Read More about Women’s football subculture of misogyny: the escalation to online gender-based violence.

The role of WSB-1 as a BRCAness biomarker in breast cancer (2023)
Thesis
Li, . C. (2023). The role of WSB-1 as a BRCAness biomarker in breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4436228

Background Radiotherapy currently has become one of the major therapeutic approaches in the treatments for cancers. However, hypoxia presents a significant challenge to the effectiveness of radiotherapy and is associated with radio-resistance. Previ... Read More about The role of WSB-1 as a BRCAness biomarker in breast cancer.

Reserving the objectionable: reprisals against enemy civilians, the United Kingdom and 1977 Additional Protocol I (2023)
Journal Article
Moir, L. (in press). Reserving the objectionable: reprisals against enemy civilians, the United Kingdom and 1977 Additional Protocol I. The Military Law and the Law of War Review, 61(2),

Belligerent reprisals are a largely discredited method for the enforcement of international humanitarian law, which have been progressively limited and prohibited. Additional Protocol I of 1977 prohibits reprisals against enemy civilians but the Unit... Read More about Reserving the objectionable: reprisals against enemy civilians, the United Kingdom and 1977 Additional Protocol I.

Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice (2023)
Journal Article
Aryankhesal, A., Blake, J., Wong, G., Megson, M., Briscoe, S., Allan, L., …Fox, C. (in press). Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice. The British journal of general practice : the journal of the Royal College of General Practitioners, https://doi.org/10.3399/BJGP.2023.0171

Background Sleep disturbance (SD) is a prevalent condition among people living with dementia (PLwD) or mild cognitive impairment (MCI). Its assessment and management within primary care is complex due to the comorbidities, older age and cognitive im... Read More about Sleep disturbance in dementia or mild cognitive impairment: a realist review of general practice.

The black widow pulsar J1641+8049 in the optical, radio, and X-rays (2023)
Journal Article
Kirichenko, A. Y., Zharikov, S. V., Karpova, A. V., Fonseca, E., Zyuzin, D. A., Shibanov, Y. A., …Swiggum, J. K. (2024). The black widow pulsar J1641+8049 in the optical, radio, and X-rays. Monthly notices of the Royal Astronomical Society, 527(3), 4563-4572. https://doi.org/10.1093/mnras/stad3391

PSR J1641+8049 is a 2 ms black widow pulsar with the 2.2 h orbital period detected in the radio and γ -rays. We performed new phase-resolved multiband photometry of PSR J1641+8049 using the OSIRIS instrument at the Gran Telescopio Canarias. The obtai... Read More about The black widow pulsar J1641+8049 in the optical, radio, and X-rays.

Improved traceability in seafood supply chains is achievable by minimising vulnerable nodes in processing and distribution networks (2023)
Journal Article
Hopkins, C. R., Roberts, S. I., Caveen, A. J., Graham, C., & Burns, N. M. (2024). Improved traceability in seafood supply chains is achievable by minimising vulnerable nodes in processing and distribution networks. Marine Policy, 159, Article 105910. https://doi.org/10.1016/j.marpol.2023.105910

Seafood is a globally traded commodity, often involving complex supply chains which have varying degrees of traceability. A robust traceability system for seafood supply chains enables the collection and communication of key information about catch a... Read More about Improved traceability in seafood supply chains is achievable by minimising vulnerable nodes in processing and distribution networks.

Molecular Analysis at Relapse of Patients Treated on the Ibrutinib and Rituximab Arm of the National Multi-Centre Phase III FLAIR Study in Previously Untreated CLL Patients (2023)
Journal Article
Sarma, A., Evans, C., Dalal, S., Webster, N., Rawstron, A., Shingles, J., …Hillmen, P. (2023). Molecular Analysis at Relapse of Patients Treated on the Ibrutinib and Rituximab Arm of the National Multi-Centre Phase III FLAIR Study in Previously Untreated CLL Patients. Blood, 142(Supplement 1), 4636-4636. https://doi.org/10.1182/blood-2023-188597

Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict <0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial (2023)
Journal Article
Rawstron, A., Webster, N., Dalal, S., de Tute, R. M., Bell, S., Cairns, D. A., …Hillmen, P. (2023). Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict <0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial. Blood, 142(Supplement 1), 632-632. https://doi.org/10.1182/blood-2023-187943

Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study (2023)
Journal Article
Hillmen, P., Cairns, D. A., Bloor, A. J. C., Allsup, D., Cwynarski, K., Pettitt, A., …Munir, T. (2023). Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study. Blood, 142(Supplement 1), 631. https://doi.org/10.1182/blood-2023-178298

Introduction: Ibrutinib (I), an irreversible Btk inhibitor, and venetoclax (V), a Bcl-2 inhibitor, improve CLL outcomes in trials compared to chemoimmunotherapy. I and V target two key pathophysiological pathways in CLL and should be synergistic. Thi... Read More about Ibrutinib Plus Venetoclax with MRD-Directed Duration of Treatment Is Superior to FCR and Is a New Standard of Care for Previously Untreated CLL: Report of the Phase III UK NCRI FLAIR Study.

Characterisation of Novel and High Performing Double-Sided Microporous-Layers-Coated Gas Diffusion Layers for Polymer Electrolyte Membrane Fuel Cells (2023)
Journal Article
Ruscillo, F., Zhang, K., Ismail, M. S., Hughes, K. J., Ingham, D. B., Ma, L., & Pourkashanian, M. (2023). Characterisation of Novel and High Performing Double-Sided Microporous-Layers-Coated Gas Diffusion Layers for Polymer Electrolyte Membrane Fuel Cells. Energies, 16(22), Article 7601. https://doi.org/10.3390/en16227601

This study aims to experimentally evaluate the impact of a double-sided microporous layer coating on gas diffusion layers in terms of their key properties and fuel cell performance, in comparison to conventional single-sided coated gas diffusion laye... Read More about Characterisation of Novel and High Performing Double-Sided Microporous-Layers-Coated Gas Diffusion Layers for Polymer Electrolyte Membrane Fuel Cells.

BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping (2023)
Journal Article
Clark, J., Salins, N., Pearson, M., Spathis, A., Currow, D. C., Williams, S., & Johnson, M. (2023). BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping. PLoS ONE, 18(11 November), Article e0293918. https://doi.org/10.1371/journal.pone.0293918

Background Breathlessness that persists despite treatment of causal disease(s) is disabling, associated with high therapy-related costs and poor socioeconomic outcomes. Low resource countries bear a disproportionate burden of respiratory problems, of... Read More about BREATHLEssness in INDIA (BREATHE-INDIA)–Study protocol for the co-design of a community breathlessness intervention in India using realist methods and intervention mapping.

Conversations on grief and hope: a collaborative autoethnographic account exploring the lifeworlds of international youth engaged with climate action (2023)
Journal Article
Jones, L., Parsons, K. J., Halstead, F., Ngoc Nguyen, D. N., Pham, H. T., Pham, D. L., …Parsons, D. R. (2023). Conversations on grief and hope: a collaborative autoethnographic account exploring the lifeworlds of international youth engaged with climate action. Journal of the British Academy, 11(S3), 69-117. https://doi.org/10.5871/JBA/011S3.069

This paper explores the lifeworlds of international youth involved in climate and/or environmental social action, narratives that have been largely absent from a literature that has tended to focus on ‘traditional’ youth activists located in the urba... Read More about Conversations on grief and hope: a collaborative autoethnographic account exploring the lifeworlds of international youth engaged with climate action.

Implementation lessons learnt when evaluating palliative care interventions in the intensive care unit: relationships between implementation determinants, strategies, and models of delivery (2023)
Thesis
Meddick-Dyson, S. (2023). Implementation lessons learnt when evaluating palliative care interventions in the intensive care unit: relationships between implementation determinants, strategies, and models of delivery. (Thesis). Hull York Medical School. Retrieved from https://hull-repository.worktribe.com/output/4587991

Background Palliative and end-of-life care have important roles in intensive care units (ICUs) given symptom burden and rate of mortality in ICUs. However, we do not know how ICU-based palliative care interventions should be implemented. This system... Read More about Implementation lessons learnt when evaluating palliative care interventions in the intensive care unit: relationships between implementation determinants, strategies, and models of delivery.

A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails (2023)
Journal Article
Machacek, M. E., Jones, C., Kraft, R. P., Forman, W. R., Roediger, E., Sheardown, A., & Wan, J. T. (2023). A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails. The Astrophysical journal, 958(1), Article 93. https://doi.org/10.3847/1538-4357/ad00b2

Analyses of major group mergers are key to understanding the evolution of large-scale structure in the Universe and the microphysical properties of the hot gas in these systems. We present imaging and spectral analyses of deep Chandra observations of... Read More about A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails.

Sex-related responses of blue mussels to the plasticiser DEHP under climate change scenarios (2023)
Thesis
Mincarelli, L. F. (2023). Sex-related responses of blue mussels to the plasticiser DEHP under climate change scenarios. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4436320

Climate change and plastic pollution are both pressing environmental issues. Little is known, however, about the combined effect of climate change conditions (such as global warming and ocean acidification) and plastic contaminants (such as the addit... Read More about Sex-related responses of blue mussels to the plasticiser DEHP under climate change scenarios.

GTC Follow-up Observations of Very Metal-poor Star Candidates from DESI (2023)
Journal Article
Allende Prieto, C., Aguado, D. S., González Hernández, J. I., Rebolo, R., Najita, J., Manser, C. J., …Zou, H. (2023). GTC Follow-up Observations of Very Metal-poor Star Candidates from DESI. The Astrophysical journal, 957(2), Article 76. https://doi.org/10.3847/1538-4357/acfa96

The observations from the Dark Energy Spectroscopic Instrument (DESI) will significantly increase the numbers of known extremely metal-poor stars by a factor of ~10, improving the sample statistics to study the early chemical evolution of the Milky W... Read More about GTC Follow-up Observations of Very Metal-poor Star Candidates from DESI.

Comprehensive process simulation of a biomass-based hydrogen production system through gasification within the BECCS concept in a commercial two-stage fixed bed gasifier (2023)
Journal Article
Rabea, K., Michailos, S., Hughes, K. J., Ingham, D., & Pourkashanian, M. (2023). Comprehensive process simulation of a biomass-based hydrogen production system through gasification within the BECCS concept in a commercial two-stage fixed bed gasifier. Energy Conversion and Management, 298, Article 117812. https://doi.org/10.1016/j.enconman.2023.117812

Hydrogen production through biomass gasification coupled with carbon capture has the potential to be a net negative emission process. Among the different designs of biomass gasifiers, the two-stage fixed bed gasifier has proved its ability to produce... Read More about Comprehensive process simulation of a biomass-based hydrogen production system through gasification within the BECCS concept in a commercial two-stage fixed bed gasifier.

Brazil’s Strategic Diplomacy Failures and Foreign Policy Underachievement under Bolsonaro (2023)
Journal Article
Doctor, M. (2023). Brazil’s Strategic Diplomacy Failures and Foreign Policy Underachievement under Bolsonaro. Revista Brasileira de Política Internacional, 66(1), https://doi.org/10.1590/0034-7329202300111

The article examines the extent of foreign policy continuity or change and level of foreign policy achievement or underachievement during the Bolsonaro presidency. These are analysed through the lens of ‘strategic diplomacy’, a concept that considers... Read More about Brazil’s Strategic Diplomacy Failures and Foreign Policy Underachievement under Bolsonaro.