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All Outputs (20)

Paper microfluidic sensors towards on-site environmental analysis of soil nutrients (2024)
Thesis
Al Hinai, S. (2023). Paper microfluidic sensors towards on-site environmental analysis of soil nutrients. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4617797

The increase in the world population leads to an increase in the need for production of crops. To optimise crop production fertilizer application needs to be managed by the farmer, consequently, regular information about the chemistry of the soil is... Read More about Paper microfluidic sensors towards on-site environmental analysis of soil nutrients.

Novel Synthesis Methods For the Production of Human Circulating Metabolites of Natural Products (2024)
Thesis
Doyle, B. (2023). Novel Synthesis Methods For the Production of Human Circulating Metabolites of Natural Products. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4587910

Upon entering the body, any given xenobiotic can undergo metabolism which facilitates its excretion from the body. When metabolised, a compound typically has the same effects of the initial drug/nutraceutical, however this is not always the case and... Read More about Novel Synthesis Methods For the Production of Human Circulating Metabolites of Natural Products.

Development of analytical workflows for measurement of metal pollution in freshwater with citizen scientists (2023)
Thesis
Sari, M. (2023). Development of analytical workflows for measurement of metal pollution in freshwater with citizen scientists. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4459145

The emergence of heavy metals, such as nickel (Ni2+) and zinc (Zn2+), as freshwater contaminant poses an environmental and public health risk. However, the current monitoring process lacks robustness and the spatiotemporal range, impeded by relativel... Read More about Development of analytical workflows for measurement of metal pollution in freshwater with citizen scientists.

Development of a skin-on-a-chip platform for the study of wound healing (2022)
Thesis
Talar, K. (2022). Development of a skin-on-a-chip platform for the study of wound healing. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4508234

Wound healing abnormalities and non-healing chronic wounds are a major clinical problem, primarily affecting diabetic and elderly patients. Wound management associated costs resulted in a £5.3 billion financial burden to the NHS between 2012 and 2013... Read More about Development of a skin-on-a-chip platform for the study of wound healing.

Microcapsule synthesis for 3D printing of self-healing materials (2021)
Thesis
Sanders, P. (2021). Microcapsule synthesis for 3D printing of self-healing materials. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223143

3D printing allows for the manufacture of finished structures from starting components with essentially no specialist training required. The process is autonomous; the starting components, such as inks, are poured into the machine and the finished pr... Read More about Microcapsule synthesis for 3D printing of self-healing materials.

Focusing and delivery of laser radiation for nano- and microfabrication (2020)
Thesis
Al-Jarwany, Q. A. (2020). Focusing and delivery of laser radiation for nano- and microfabrication. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223093

The recent advances in nanotechnology and nanofabrication motivate the drive to achieve a tighter focusing of light; this requires a high numerical aperture (NA) optical system. The need for high optical resolution has led scientists to discover the... Read More about Focusing and delivery of laser radiation for nano- and microfabrication.

Development of a dual flow microfluidic device for the study of barrier systems (2020)
Thesis
Baldwin, L. (2020). Development of a dual flow microfluidic device for the study of barrier systems. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4223404

Inflammatory Bowel Diseases (IBD) including Crohn’s Disease and Ulcerative Colitis are chronic conditions characterised by inflammation of the wall of the gastrointestinal tract. IBD has also been shown to have systemic impacts including on the centr... Read More about Development of a dual flow microfluidic device for the study of barrier systems.

The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation (2020)
Thesis
Stinson, R. J. (2020). The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222863

Human Rhinovirus (hRV) is a major cause of upper respiratory tract infections (URTIs) and is linked to lower respiratory tract infections (LRTIs) and airway diseases exacerbations. Cough, airway inflammation and hypersensation are common symptoms of... Read More about The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation.

Developing a novel spheroid-on-chip microfluidic device for investigations into metastasis (2019)
Thesis
Collins, T. C. (2019). Developing a novel spheroid-on-chip microfluidic device for investigations into metastasis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4221851

One in two people born after 1960 will develop cancer, with 90% of all cancer deaths arising from metastasis. Conventional 2D in vitro metastasis models do not fully replicate tumour complexity. In vivo models can address tumour complexity, but do no... Read More about Developing a novel spheroid-on-chip microfluidic device for investigations into metastasis.

A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects (2019)
Journal Article
Ghobaei Namhil, Z., Kemp, C., Verrelli, E., Iles, A., Pamme, N., Adawi, A. M., & Kemp, N. (2019). A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects. Physical chemistry chemical physics : PCCP, 21(2), 681-691. https://doi.org/10.1039/c8cp05510f

A significant impediment to the use of impedance spectroscopy in bio-sensing is the electrode polarization effect that arises from the movement of free ions to the electrode-solution interface, forming an electrical double layer (EDL). The EDL screen... Read More about A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects.

Optical sensor for the analysis of biomarkers (2018)
Thesis
Al-Shemary, R. S. (2018). Optical sensor for the analysis of biomarkers. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220996

The continuous measurement of biomarkers such as proteins and hormones in blood and serum are the cornerstone of healthcare monitoring and optimising treatment plans. Often such biomarkers are present in minute concentrations. Conventional analysis m... Read More about Optical sensor for the analysis of biomarkers.

Nanogap capacitive biosensor for label-free aptamer-based protein detection (2018)
Thesis
Namhil, Z. G. (2018). Nanogap capacitive biosensor for label-free aptamer-based protein detection. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220514

Recent advances in nanotechnology offer a new platform for the label free detection of biomolecules at ultra-low concentrations. Nano biosensors are emerging as a powerful method of improving device performance whilst minimizing device size, cost and... Read More about Nanogap capacitive biosensor for label-free aptamer-based protein detection.

Surface enhanced Raman spectroscopy for single molecule detection and biosensing (2017)
Thesis
Marshall, A. R. L. (2017). Surface enhanced Raman spectroscopy for single molecule detection and biosensing. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220864

The aim of this thesis is to design plasmonic nano-gaps capable of detecting materials down to sufficiently low concentrations such that single molecule characteristics are observed. We begin first, by discussing the theory of plasmonics. Then, we as... Read More about Surface enhanced Raman spectroscopy for single molecule detection and biosensing.

Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems (2016)
Thesis
Chowdhury, M. M. U. (2016). Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219336

The work described in this thesis, concerns developments to analytical microfluidic Lab-On-Chip platform originally developed by Prof Pamme's research group at the University of Hull. This work aims to move away from traditional laboratory analysis s... Read More about Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems.

Development of a combined DNA and drug extraction methodology for forensic toxicology application (2014)
Thesis
Kashkary, L. M. T. (2014). Development of a combined DNA and drug extraction methodology for forensic toxicology application. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4217177

Biological samples recovered at crime scenes may contain unsuspected and valuable evidence, such as illicit drugs, in addition to nucleic acids. Deoxyribonucleic acid (DNA) analysis provides valuable information to identify a suspect or victim, as we... Read More about Development of a combined DNA and drug extraction methodology for forensic toxicology application.

Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications (2012)
Thesis
Lumley, E. K. (2012). Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219891

Cancer cells are derived from cells that are termed, and recognised as being 'self', meaning that the immune system does not target them. Many treatments target the tumour through its requirement for large quantities of nutrients. However, this cause... Read More about Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications.

Microfluidic modules for pre-concentration of [¹⁸F]fluoride in positron emission tomography (PET) radiotracer synthesis (2012)
Thesis
De Leonardis, F. (2012). Microfluidic modules for pre-concentration of [¹⁸F]fluoride in positron emission tomography (PET) radiotracer synthesis. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4214123

lPositron Emission Tomography (PET) is a non-invasive imaging method which enables to obtain both molecular and biochemical information of physiological processes in vivo, which means that PET imaging shows the chemical functioning of organs and tiss... Read More about Microfluidic modules for pre-concentration of [¹⁸F]fluoride in positron emission tomography (PET) radiotracer synthesis.

Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices (2011)
Thesis
Tarn, M. D. (2011). Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4211533

Magnetic microparticles have seen increasing interest in (bio)chemical processes in recent years due to their various surface functionalities, high surface-to-volume ratio, small sizes, and ease of manipulation via magnetic fields. However, conventio... Read More about Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices.

Magnetic forces for surface-based bioanalysis in microfluidic devices (2010)
Thesis
Peyman, S. A. (2010). Magnetic forces for surface-based bioanalysis in microfluidic devices. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4213006

Biochemical analysis is a critical part of clinical diagnostics, forensic science and environmental monitoring. Typically, this form of analysis involves the use of bioanalytical procedures which are extremely sensitive and highly specific. However,... Read More about Magnetic forces for surface-based bioanalysis in microfluidic devices.