All Outputs (4)

The generation of an immunosuppressive microenvironment by soluble factors in head and neck squamous cell carcinoma (2018)
Thesis
Roberts, E. R. (2018). The generation of an immunosuppressive microenvironment by soluble factors in head and neck squamous cell carcinoma. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4220880

Tumour infiltrating lymphocytes (TIL) in head neck squamous cell carcinoma (HNSCC) are enriched in Treg, a finding confirmed in the current study, which is thought to be a contributing factor to immunosuppression and tumour evasion. Soluble factors r... Read More about The generation of an immunosuppressive microenvironment by soluble factors in head and neck squamous cell carcinoma.

Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach (2016)
Thesis
Cheah, R. (2016). Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4218576

Radiotherapy remains the standard treat74ment for head and neck squamous cell carcinoma (HNSCC), however, resistance remains a real clinical problem despite the improvements and development of new treatment strategies. Patient outcome could potential... Read More about Monitoring the response of head and neck tumour tissue to irradiation using a microfluidic-based approach.

The effect of HNSCC-derived soluble factors on the proliferation and function of immune cells (2016)
Thesis
Smith, J. D. (2016). The effect of HNSCC-derived soluble factors on the proliferation and function of immune cells. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4219345

Malignant epithelium and associated stromal cells secrete soluble factors which may influence tumour evasion of host immunity. The effect of these factors on the proliferation and function of individual immune cell populations has been investigated a... Read More about The effect of HNSCC-derived soluble factors on the proliferation and function of immune cells.

Phenotypic and functional characterisation of regulatory T cells in head and neck squamous cell carcinoma (2013)
Thesis
Drennan, S. (2013). Phenotypic and functional characterisation of regulatory T cells in head and neck squamous cell carcinoma. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4215991

Head and neck cancer is the sixth most common cancer worldwide. Despite advances in therapy, the five year survival rate remains poor. The presence of regulatory T cells (Tregs) may be a mechanism by which head and neck squamous cell carcinoma (HNSCC... Read More about Phenotypic and functional characterisation of regulatory T cells in head and neck squamous cell carcinoma.