All Outputs (4)

Studies on skeletal muscle stem cell biology of the apolipoprotein E deficient mice (2022)
Thesis
Barlow, J. J. (2022). Studies on skeletal muscle stem cell biology of the apolipoprotein E deficient mice. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4224384

Skeletal muscle has tremendous adaptive and regenerative ability, this is achieved through a resource of stem cells which remain present in adults. These cells remain quiescent until activated by myogenic factors, at which point they proliferate and... Read More about Studies on skeletal muscle stem cell biology of the apolipoprotein E deficient mice.

Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention (2020)
Journal Article
Vaughan, D., Kretz, O., Alqallaf, A., Mitchell, R., von der Heide, J., Vaiyapuri, S., …Patel, K. (in press). Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention. European Journal of Translational Myology, 30(2), 276-285. https://doi.org/10.4081/ejtm.0.8904

Duchenne Muscular Dystrophy is a devastating disease caused by the absence of a functional rod-shaped cytoplasmic protein called dystrophin. Several avenues are being developed aimed to restore dystrophin expression in boys affected by this X-linked... Read More about Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention.

The impact on high-fat diet on skeletal muscle stem cell recruitment in CD36 deficient mice (2019)
Thesis
Verpoorten, S. (2019). The impact on high-fat diet on skeletal muscle stem cell recruitment in CD36 deficient mice. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222387

The prevalence of obesity is a major risk factor for cardiovascular and metabolic diseases including impaired skeletal muscle regeneration. Given the importance of skeletal muscle function in the context of obesity, it is paramount to understand the... Read More about The impact on high-fat diet on skeletal muscle stem cell recruitment in CD36 deficient mice.

The role of platelets in skeletal muscle regeneration (2019)
Thesis
Scully, D. (2019). The role of platelets in skeletal muscle regeneration. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4222188

Overview: Biomaterials such as autologous platelet-based applications have gained intense research interest. However, the mechanisms driving platelet‐mediated skeletal myogenesis remain to be established. Therefore, the aim of this thesis was to opti... Read More about The role of platelets in skeletal muscle regeneration.