Knee Replacement Bandaging Study (KReBS) evaluating the effect of a two-layer compression bandage system on knee function following total knee arthroplasty: study protocol for a randomised controlled trial.

Cook, Liz; Northgraves, Matthew J.; Fairhurst, Caroline; Ronaldson, Sarah; Torgerson, David J.; Kent, Jonathan; Reed, Mike

doi:10.1186/s13063-019-3344-1

Authors

Liz Cook

Dr Matthew Northgraves M.Northgraves@hull.ac.uk
Clinical Trial Manager

Caroline Fairhurst

Sarah Ronaldson

David J. Torgerson

Jonathan Kent

Mike Reed

Abstract

Background: Data from a feasibility study suggest that the use of an inelastic, short-stretch compression bandage following total knee arthroplasty is a safe technique that may improve patient-reported health outcomes, and that it is feasible to recruit to a full-scale study. Methods: We will conduct a randomised controlled trial (RCT) of 2600 adult patients, which has 80% power to detect a 1 point difference in the Oxford Knee Score (a patient self-reported assessment of knee pain and function) at 52 weeks. Short stretch compression bandaging will be compared with standard wool and crepe bandaging following total knee arthroplasty. Recruitment will take place in orthopaedic units across the United Kingdom. Secondary outcomes include the EuroQol 5 Dimensions (EQ-5D)-5 L and EQ-5D-3 L scores, pain, length of hospital stay, and complications. Discussion: The Knee Replacement Bandaging Study (KReBS) is a large study which aims to contribute to the evidence base for informing clinical decisions for the use of compression bandaging following knee arthroplasty. Trial registration: International Standard Randomised Controlled Trial Register, ISRCTN 87127065. Registered on 20 February 2017.

Citation

Cook, L., Northgraves, M. J., Fairhurst, C., Ronaldson, S., Torgerson, D. J., Kent, J., & Reed, M. (2019). Knee Replacement Bandaging Study (KReBS) evaluating the effect of a two-layer compression bandage system on knee function following total knee arthroplasty: study protocol for a randomised controlled trial. Trials, 20(1), Article 261. https://doi.org/10.1186/s13063-019-3344-1

Journal Article Type	Article
Acceptance Date	Apr 3, 2019
Online Publication Date	May 8, 2019
Publication Date	2019
Deposit Date	May 20, 2019
Publicly Available Date	May 21, 2019
Journal	Trials
Print ISSN	1745-6215
Electronic ISSN	1745-6215
Publisher	Springer Verlag
Peer Reviewed	Peer Reviewed
Volume	20
Issue	1
Article Number	261
DOI	https://doi.org/10.1186/s13063-019-3344-1
Keywords	Knee replacement; Arthroplasty; Compression bandage; Randomised controlled trial
Public URL	https://hull-repository.worktribe.com/output/1791422

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