Knee Replacement Bandaging Study (KReBS) evaluating the effect of a two-layer compression bandage system on knee function following total knee arthroplasty: study protocol for a randomised controlled trial.
Cook, L; Northgraves, MJ; Fairhurst, C; Ronaldson, S; Torgerson, DJ; Kent, J; Reed, M
Dr Matthew Northgraves M.Northgraves@hull.ac.uk
Data from a feasibility study suggest that the use of an inelastic, short-stretch compression bandage following total knee arthroplasty is a safe technique that may improve patient-reported health outcomes, and that it is feasible to recruit to a full-scale study.
We will conduct a randomised controlled trial (RCT) of 2600 adult patients, which has 80% power to detect a 1 point difference in the Oxford Knee Score (a patient self-reported assessment of knee pain and function) at 52 weeks. Short stretch compression bandaging will be compared with standard wool and crepe bandaging following total knee arthroplasty. Recruitment will take place in orthopaedic units across the United Kingdom. Secondary outcomes include the EuroQol 5 Dimensions (EQ-5D)-5 L and EQ-5D-3 L scores, pain, length of hospital stay, and complications.
The Knee Replacement Bandaging Study (KReBS) is a large study which aims to contribute to the evidence base for informing clinical decisions for the use of compression bandaging following knee arthroplasty.
International Standard Randomised Controlled Trial Register, ISRCTN 87127065. Registered on 20 February 2017.
Cook, L., Northgraves, M., Fairhurst, C., Ronaldson, S., Torgerson, D., Kent, J., & Reed, M. (2019). Knee Replacement Bandaging Study (KReBS) evaluating the effect of a two-layer compression bandage system on knee function following total knee arthroplasty: study protocol for a randomised controlled trial. Trials, 20, https://doi.org/10.1186/s13063-019-3344-1
|Journal Article Type||Article|
|Acceptance Date||Apr 3, 2019|
|Online Publication Date||May 8, 2019|
|Deposit Date||May 20, 2019|
|Publicly Available Date||May 21, 2019|
|Peer Reviewed||Peer Reviewed|
|Keywords||Knee replacement; Arthroplasty; Compression bandage; Randomised controlled trial|
Publisher Licence URL
© The Author(s). 2019 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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