A flexible tripod fluorescent probe for multiple cations detection and its application in living cells

Xu, Wan Li; Yang, Jun Feng; Ran, Mao Qian; Zeng, Xi; Redshaw, Carl; Tao, Zhu

Abstract

To the flexible tripod platform tren (tris(2-aminoethyl)amine), a Rhodamine and two naphthalene fluorophores were introduced. The resulting fluorescence probe named TRN was fully characterized and employed in cell imaging. Probe TRN exhibited high selectivity and excellent sensitivity for the simultaneous fluorescence detection of Zn2+/Hg2+/Al3+/Cu2+. The significant changes in the fluorescence color make naked-eye detection possible. Furthermore, fluorescence imaging experiments of Zn2+/Hg2+/Al3+/Cu2+ in living PC3 cells demonstrated its value for practical applications in biological systems.

Citation

Xu, W. L., Yang, J. F., Ran, M. Q., Zeng, X., Redshaw, C., & Tao, Z. (2020). A flexible tripod fluorescent probe for multiple cations detection and its application in living cells. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 240, Article 118614. https://doi.org/10.1016/j.saa.2020.118614

• Journal Article Type: Article
• Acceptance Date: Jun 9, 2020
• Online Publication Date: Jun 20, 2020
• Publication Date: Oct 15, 2020
• Deposit Date: Jun 23, 2020
• Publicly Available Date: Jun 21, 2021
• Journal: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
• Print ISSN: 1386-1425
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 240
• Article Number: 118614
• DOI: https://doi.org/10.1016/j.saa.2020.118614
• Keywords: Flexible tripod probe; Zn2+/Hg2+/Al3+/Cu2+ ions detection; Cells imaging
• Public URL: https://hull-repository.worktribe.com/output/3525329
• Publisher URL: https://www.sciencedirect.com/science/article/abs/pii/S138614252030593X?via%3Dihub