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A flexible tripod fluorescent probe for multiple cations detection and its application in living cells

Xu, Wan Li; Yang, Jun Feng; Ran, Mao Qian; Zeng, Xi; Redshaw, Carl; Tao, Zhu

Authors

Wan Li Xu

Jun Feng Yang

Mao Qian Ran

Xi Zeng

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Professor Carl Redshaw C.Redshaw@hull.ac.uk
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry

Zhu Tao



Abstract

To the flexible tripod platform tren (tris(2-aminoethyl)amine), a Rhodamine and two naphthalene fluorophores were introduced. The resulting fluorescence probe named TRN was fully characterized and employed in cell imaging. Probe TRN exhibited high selectivity and excellent sensitivity for the simultaneous fluorescence detection of Zn2+/Hg2+/Al3+/Cu2+. The significant changes in the fluorescence color make naked-eye detection possible. Furthermore, fluorescence imaging experiments of Zn2+/Hg2+/Al3+/Cu2+ in living PC3 cells demonstrated its value for practical applications in biological systems.

Citation

Xu, W. L., Yang, J. F., Ran, M. Q., Zeng, X., Redshaw, C., & Tao, Z. (2020). A flexible tripod fluorescent probe for multiple cations detection and its application in living cells. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 240, https://doi.org/10.1016/j.saa.2020.118614

Journal Article Type Article
Acceptance Date Jun 9, 2020
Online Publication Date Jun 20, 2020
Publication Date Oct 15, 2020
Deposit Date Jun 23, 2020
Publicly Available Date Jun 21, 2021
Journal Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Print ISSN 1386-1425
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 240
Article Number 118614
DOI https://doi.org/10.1016/j.saa.2020.118614
Keywords Flexible tripod probe; Zn2+/Hg2+/Al3+/Cu2+ ions detection; Cells imaging
Public URL https://hull-repository.worktribe.com/output/3525329
Publisher URL https://www.sciencedirect.com/science/article/abs/pii/S138614252030593X?via%3Dihub