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A flexible tripod fluorescent probe for multiple cations detection and its application in living cells

Xu, Wan-Li; Yang, Jun-Feng; Ran, Mao-Qian; Zeng, Xi; Redshaw, Carl; Tao, Zhu

Authors

Wan-Li Xu

Jun-Feng Yang

Mao-Qian Ran

Xi Zeng

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Professor Carl Redshaw C.Redshaw@hull.ac.uk
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry

Zhu Tao



Abstract

To the flexible tripod platform tren (tris(2-aminoethyl)amine), a Rhodamine and two naphthalene fluorophores were introduced. The resulting fluorescence probe named TRN was fully characterized and employed in cell imaging. Probe TRN exhibited high selectivity and excellent sensitivity for the simultaneous fluorescence detection of Zn2+/Hg2+/Al3+/Cu2+. The significant changes in the fluorescence color make naked-eye detection possible. Furthermore, fluorescence imaging experiments of Zn2+/Hg2+/Al3+/Cu2+ in living PC3 cells demonstrated its value for practical applications in biological systems.

Journal Article Type Article
Journal Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Print ISSN 1386-1425
Publisher Elsevier
Peer Reviewed Peer Reviewed
Article Number 118614
APA6 Citation Xu, W., Yang, J., Ran, M., Zeng, X., Redshaw, C., & Tao, Z. (in press). A flexible tripod fluorescent probe for multiple cations detection and its application in living cells. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, https://doi.org/10.1016/j.saa.2020.118614
DOI https://doi.org/10.1016/j.saa.2020.118614
Keywords Flexible tripod probe; Zn2+/Hg2+/Al3+/Cu2+ ions detection; Cells imaging
Publisher URL https://www.sciencedirect.com/science/article/abs/pii/S138614252030593X?via%3Dihub
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