A flexible tripod fluorescent probe for multiple cations detection and its application in living cells
Xu, Wan-Li; Yang, Jun-Feng; Ran, Mao-Qian; Zeng, Xi; Redshaw, Carl; Tao, Zhu
Professor Carl Redshaw C.Redshaw@hull.ac.uk
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry
To the flexible tripod platform tren (tris(2-aminoethyl)amine), a Rhodamine and two naphthalene fluorophores were introduced. The resulting fluorescence probe named TRN was fully characterized and employed in cell imaging. Probe TRN exhibited high selectivity and excellent sensitivity for the simultaneous fluorescence detection of Zn2+/Hg2+/Al3+/Cu2+. The significant changes in the fluorescence color make naked-eye detection possible. Furthermore, fluorescence imaging experiments of Zn2+/Hg2+/Al3+/Cu2+ in living PC3 cells demonstrated its value for practical applications in biological systems.
|Journal Article Type||Article|
|Journal||Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy|
|Peer Reviewed||Peer Reviewed|
|APA6 Citation||Xu, W., Yang, J., Ran, M., Zeng, X., Redshaw, C., & Tao, Z. (in press). A flexible tripod fluorescent probe for multiple cations detection and its application in living cells. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, https://doi.org/10.1016/j.saa.2020.118614|
|Keywords||Flexible tripod probe; Zn2+/Hg2+/Al3+/Cu2+ ions detection; Cells imaging|
This file is under embargo until Jun 21, 2021 due to copyright reasons.
Contact C.Redshaw@hull.ac.uk to request a copy for personal use.
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