Priyadharshanan Ariyaratnam
Hypoxic pulmonary vasoconstriction in humans
Ariyaratnam, Priyadharshanan; Loubani, Mahmoud; Morice, Alyn H.
Authors
Mahmoud Loubani
Professor Alyn Morice A.H.Morice@hull.ac.uk
Foundation Chair and Professor of Respiratory Medicine
Abstract
Hypoxic pulmonary vasoconstriction is the elegant theory put forward more than six decades ago to explain regional variations in perfusion within the lung in certain animal species in response to localised restrictions in oxygenation. Although considerable progress has been made to describe the phenomenon at the macroscopic level and explain it at the microscopic level, we are far from a universal agreement about the process in humans. This review attempts to highlight some of the important evidence bases of hypoxic pulmonary vasoconstriction in humans and the significant gaps in our knowledge that would need bridging. © 2013 Priyadharshanan Ariyaratnam et al.
Citation
Ariyaratnam, P., Loubani, M., & Morice, A. H. (2013). Hypoxic pulmonary vasoconstriction in humans. Biomed research international, 2013, Article 623684. https://doi.org/10.1155/2013/623684
Journal Article Type | Review |
---|---|
Acceptance Date | Jul 22, 2013 |
Online Publication Date | Aug 20, 2013 |
Publication Date | Sep 23, 2013 |
Deposit Date | May 23, 2022 |
Publicly Available Date | May 27, 2022 |
Journal | BioMed Research International |
Print ISSN | 2314-6133 |
Publisher | Hindawi |
Peer Reviewed | Peer Reviewed |
Volume | 2013 |
Article Number | 623684 |
DOI | https://doi.org/10.1155/2013/623684 |
Public URL | https://hull-repository.worktribe.com/output/3610168 |
Files
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Publisher Licence URL
http://creativecommons.org/licenses/by/4.0
Copyright Statement
Copyright © 2013 Priyadharshanan Ariyaratnam et al. This is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is
properly cited.
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