Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology

Pathmanathan, Sega; Morjaria, Jaymin B.; Morice, Alyn H.; Jackson, Warren

Abstract

Chronic cough is a common symptom carrying significant morbidity which can occur as a result of oesophageal dysmotility. Here we report 2 patients with musculoskeletal disease presenting with chronic cough to our tertiary cough clinic. Prior to referral both patients had been extensively investigated to determine the basis of their cough, with no cause found. Oesophageal studies, using high resolution oesophageal manometry, demonstrated oesophageal dysmotility with consequent airway reflux. Anti-reflux therapy resulted in a good response in both patients. These are the first reports of the recently developed technique of high resolution manometry aiding the diagnosis of chronic cough. This technique may provide important clues into aetiological mechanism in patients with conditions predisposing to reflux into the airways. © 2012 Pathmanathan et al.; licensee BioMed Central Ltd.

Citation

Pathmanathan, S., Morjaria, J. B., Morice, A. H., & Jackson, W. (2012). Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology. Cough, 8(1), 6. https://doi.org/10.1186/1745-9974-8-6

• Journal Article Type: Article
• Acceptance Date: Sep 7, 2012
• Online Publication Date: Sep 28, 2012
• Publication Date: Sep 28, 2012
• Deposit Date: May 23, 2022
• Publicly Available Date: Sep 9, 2022
• Journal: Cough
• Print ISSN: 1745-9974
• Publisher: BioMed Central
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 1
• Article Number: 6
• DOI: https://doi.org/10.1186/1745-9974-8-6
• Keywords: Chronic cough; Airway reflux; Ehlers-Danlos; Dermatomyositis
• Public URL: https://hull-repository.worktribe.com/output/3610208