As the workforce in the British National Health Service (NHS) has become more diverse, several researchers have reported that experiences of overseas’ nurses have been largely negative. This paper explores black African nurses’ experiences of equal opportunities, racism, and discrimination in four NHS trusts in the North East of England. Thirty nurses from sub-Saharan countries working in four NHS trusts were interviewed between 2006 and 2008 using semi-structured interviews and focus group discussions to gain an insight into their experiences in the NHS. This study suggests that black African nurses experienced discrimination and racism emanating from white colleagues and other overseas nurses, managers, patients, and their relatives, as well as lack of opportunities in their workplaces. Managers seemed to be treating British and other overseas nurses more favorably than black African nurses. Although much progress has been made in valuing and embracing diversity in the NHS, this paper highlights areas in which more work is required.