Diabetes mellitus is a growing health challenge globally which is increasing in epidemic proportion. Naturally occurring pharmacological agents are more likely to provide beneficial therapeutic effects without undesirable side effects compared to the synthetic agents. There is a growing evidence that some naturally occurring pharmacological agents derived from plants have potential antihyperglycemic effects. In this study, we have reviewed the molecular mechanism behind potential hypoglycemic properties of four well-known herbal-based agents, namely, ginger, curcumin, garlic, and cinnamon. Also, we present the related clinical data confirming experimental results aiming to develop novel therapeutic strategies based on these herbal agents potentially for the management of patients with diabetes.
Citation
Yaribeygi, H., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2021). Natural Insulin Sensitizers for the Management of Diabetes Mellitus: A Review of Possible Molecular Mechanisms. In A. Sahebkar, & T. Sathyapalan (Eds.), Natural Products and Human Diseases (401-410). Springer. https://doi.org/10.1007/978-3-030-73234-9_26
Online Publication Date
Jan 3, 2022
Publication Date
Jan 1, 2021
Deposit Date
Aug 29, 2022
Publicly Available Date
Jan 2, 2023
Publisher
Springer
Pages
401-410
Series Title
Advances in Experimental Medicine and Biology : Proteomics, Metabolomics, Interactomics and Systems Biology
