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Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data

Hitchman, Louise; Machin, Matthew


Louise Hitchman

Matthew Machin


BACKGROUND: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. it found that perioperative COVID-19 infection was associated with a mortality rate of 24%. at the same time, the COVER study demonstrated similarly high perioperative mortality rates in vascular surgical patients undergoing vascular interventions even without COVID-19, likely associated with the high burden of comorbidity associated with vascular patients. This is a vascular subgroup analysis of the COVIDSurg cohort.
METHODS: All patients with a suspected or confirmed diagnosis of COVID-19 in the 7 days prior to, or in the 30 days following a vascular procedure were included. The primary outcome was 30-day mortality. Secondary outcomes were pulmonary complications (adult respiratory distress syndrome, pulmonary embolism, pneumonia and respiratory failure). logistic regression was undertaken for dichotomous outcomes.
RESULTS: overall, 602 patients were included in this subgroup analysis, of which 88.4% were emergencies. The most common operations performed were for vascular-related dialysis access procedures (20.1%, N.=121). The combined 30-day mortality rate was 27.2%. Composite secondary pulmonary outcomes occurred in half of the vascular patients (N.=275, 45.7%).
CONCLUSIONS: Mortality following vascular surgery in COVID positive patients was significantly higher than levels reported pre-pandemic, and similar to that seen in other specialties in the COVIDSurg cohort. initiatives and surgical pathways that ensure vascular patients are protected from exposure to COVID-19 in the peri-operative period are vital to protect against excess mortality.


Hitchman, L., & Machin, M. (2021). Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data. Journal of Cardiovascular Surgery, 62(6), 558-70.

Journal Article Type Article
Acceptance Date Oct 13, 2021
Publication Date 2021-12
Deposit Date Jan 25, 2022
Publicly Available Date Jan 1, 2023
Journal Journal of Cardiovascular Surgery
Publisher Edizioni Minerva Medica
Peer Reviewed Peer Reviewed
Volume 62
Issue 6
Pages 558-70
Keywords COVID-19; Vascular surgical procedures; Health care outcome assessment
Public URL
Additional Information Free access on publisher website (Feb 2022)


Accepted manuscript (383 Kb)

Copyright Statement
This is a postprint version of the article published in The Journal of Cardiovascular Surgery. This version is free to view and download to private research and study only. Not for redistribution or re-use. ©Edizioni Minerva Medica. The final published article is available online on Minerva Medica website at Cite this article as Hitchman L, Machin M; The COVIDSurg Collaborative and Vascular and Endovascular Research Network. Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data. J Cardiovasc Surg 2021;62:558-70.

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