Yang Luo
A new cucurbit[10]uril-based AIE fluorescent supramolecular polymer for cellular imaging
Luo, Yang; Gan, Shiquan; Zhang, Wei; Jia, Menghao; Chen, Lixia; Redshaw, Carl; Tao, Zhu; Xiao, Xin
Authors
Shiquan Gan
Wei Zhang
Menghao Jia
Lixia Chen
Professor Carl Redshaw C.Redshaw@hull.ac.uk
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry
Zhu Tao
Xin Xiao
Abstract
To further advance the development of cucurbit[10]uril-based supramolecular biomaterials, an AIE fluorescent supramolecular polymer (TPE-B@Q[10]) was constructed from the newly synthesized AIE molecule TPE-B and Q[10] via host-guest interactions in a host/guest ratio of 2: 1. TPE-B@Q[10] not only has excellent blue fluorescence emission properties, but also possesses good biocompatibility and low toxicity. Therefore, TPE-B@Q[10] was successfully used for cytoplasmic imaging of cells. Flow cytometry further illustrated that Q[10] is capable of generating an alternative way to increase the fluorescence of TPE-B and its characteristic pattern for cellular imaging. This work provides a theoretical basis for promoting the application of cucurbit[n]uril-based supramolecular polymers in cell biology, and promotes the further development of cucurbit[n]uril chemistry.
Citation
Luo, Y., Gan, S., Zhang, W., Jia, M., Chen, L., Redshaw, C., …Xiao, X. (2022). A new cucurbit[10]uril-based AIE fluorescent supramolecular polymer for cellular imaging. Materials Chemistry Frontiers, 6(8), 1021-1025. https://doi.org/10.1039/d2qm00084a
Journal Article Type | Article |
---|---|
Acceptance Date | Feb 22, 2022 |
Online Publication Date | Feb 22, 2022 |
Publication Date | Apr 21, 2022 |
Deposit Date | Mar 13, 2022 |
Publicly Available Date | Feb 23, 2023 |
Journal | Materials Chemistry Frontiers |
Print ISSN | 2052-1537 |
Electronic ISSN | 2052-1537 |
Publisher | Royal Society of Chemistry |
Peer Reviewed | Peer Reviewed |
Volume | 6 |
Issue | 8 |
Pages | 1021-1025 |
DOI | https://doi.org/10.1039/d2qm00084a |
Keywords | Materials Chemistry; General Materials Science |
Public URL | https://hull-repository.worktribe.com/output/3938570 |
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Copyright Statement
©2022 The authors. All rights reserved. No part of this publication may be reproduced without the written permission of the copyright holder
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