Resolution of secondary arylalkyl alcohols using pentafluorophenyl 2-phenylbutanoate and zinc chloride

Coulbeck, Elliot; Eames, Jason

Abstract

The resolution of racemic secondary arylalkyl alcohols using pentafluorophenyl 2-phenylbutanoate and zinc chloride is discussed. The levels of enantiomeric recognition were high leading to enantiomerically enriched alcohols in good yield. © 2009 Elsevier Ltd. All rights reserved.

Citation

Coulbeck, E., & Eames, J. (2009). Resolution of secondary arylalkyl alcohols using pentafluorophenyl 2-phenylbutanoate and zinc chloride. Tetrahedron letters; the international organ for the rapid publication of preliminary communications in organic chemistry, 50(31), 4449-4451. https://doi.org/10.1016/j.tetlet.2009.05.046

• Journal Article Type: Article
• Acceptance Date: May 15, 2009
• Online Publication Date: May 22, 2009
• Publication Date: Aug 5, 2009
• Journal: TETRAHEDRON LETTERS
• Print ISSN: 0040-4039
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 50
• Issue: 31
• Pages: 4449-4451
• DOI: https://doi.org/10.1016/j.tetlet.2009.05.046
• Keywords: Organic Chemistry; Biochemistry; Drug Discovery
• Public URL: https://hull-repository.worktribe.com/output/395912
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S004040390901048X?via%3Dihub