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The DEFINITE Audit - A Prospective Audit of Diabetic Foot Debridement in Theatre: A Protocol

Hitchman, Louise


Louise Hitchman


People with diabetes are commonly affected by foot ulceration (DFU) and subsequent or concurrent infection (DFI). Surgical debridement is often needed to contain infection. Despite international guidelines, there remains significant variation in surgical practice of diabetic foot wound debridement in the operating theatre.

Diabetic Foot Ulcer Debridement in Theatre Audit (DEFINITE) is a global multicentre, prospective audit of consecutive patients undergoing a debridement or minor amputation in theatre for a diabetic foot complication. DEFINITE is led by the Vascular and Endovascular Research Network (VERN).
The primary outcome is adherence to recommended practice as outlined in the International Working Group on the Diabetic Foot and Global Vascular Guidelines. Secondary outcomes are incidence of healing, re-admission, further amputation (minor and major) and mortality at 90 days. Anonymised data will be collected via REDCap.
All hospital institutions performing in-theatre management of diabetic foot complications are eligible to participate after obtaining appropriate institutional level audit approvals. A lead clinician will be responsible for approvals and data management.

Pathway to impact
This audit addresses shared patient-clinician priorities and is supported by the UK Vascular Society multidisciplinary Special Interest Group on the Diabetic Foot. The results will be presented at international scientific meetings and submitted for publication in peer reviewed publications. The results will also be used to initiate improvement in patient care.


Hitchman, L. (in press). The DEFINITE Audit - A Prospective Audit of Diabetic Foot Debridement in Theatre: A Protocol. Journal of Vascular Societies Great Britain and Ireland,

Journal Article Type Article
Acceptance Date Oct 11, 2022
Deposit Date Nov 17, 2022
Publisher Vascular Society for Great Britain and Ireland
Peer Reviewed Peer Reviewed
Public URL