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Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol

Liu, Ben; Sharma, Abhiram; Waudby, Philip; Duthie, Graeme S.

Authors

Ben Liu

Abhiram Sharma

Philip Waudby

Graeme S. Duthie G.S.Duthie@hull.ac.uk



Abstract

Background
Constipation is a common multifactorial gastrointestinal symptom with quality of life implications. Sacral neuromodulation has been used in the management of severe constipation with mixed results. The aim of this study was to review our experience of sacral neuromodulation as a treatment for chronic constipation and develop a chronic constipation management protocol.
Methods
In patients with severe constipation, failure of conservative management including biofeedback and rectal irrigation were considered for neuromodulation. Temporary stimulation lead was placed in the sacral foramen of eligible patients and pre and post stimulation bowel diaries were compared. Patients with ≥50% improvement in bowel diaries had permanent implant. Patients were followed up at 2 and 4weeks, 3, 6, and 12months, and then yearly with bowel diaries.
Results
Temporary neuromodulation wires were implanted in 21 patients (20 female). Significant bowel diary improvement was seen in 12 (57%) patients (p 

Journal Article Type Article
Publication Date 2011-12
Journal INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
Print ISSN 0179-1958
Electronic ISSN 1432-1262
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 26
Issue 12
Pages 1583-1587
APA6 Citation Sharma, A., Liu, B., Waudby, P., & Duthie, G. S. (2011). Sacral neuromodulation for the management of severe constipation: development of a constipation treatment protocol. International Journal of Colorectal Disease, 26(12), (1583-1587). doi:10.1007/s00384-011-1257-x. ISSN 0179-1958
DOI https://doi.org/10.1007/s00384-011-1257-x
Keywords Sacral neuromodulation; Sacral nerve stimulation; Constipation
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