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Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

Redshaw, Carl; Elsegood, Mark R. J.; Wright, Joseph A.; Baillie-Johnson, Hugo; Yamato, Takehiko; Giovanni, Stephen De; Mueller, Anja


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Professor Carl Redshaw
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry

Mark R. J. Elsegood

Joseph A. Wright

Hugo Baillie-Johnson

Takehiko Yamato

Stephen De Giovanni

Anja Mueller


Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.


Redshaw, C., Elsegood, M. R. J., Wright, J. A., Baillie-Johnson, H., Yamato, T., Giovanni, S. D., & Mueller, A. (2012). Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene. Chemical communications : Chem comm / the Royal Society of Chemistry, 48(8), 1129-1131.

Journal Article Type Article
Acceptance Date Nov 23, 2011
Online Publication Date Nov 24, 2011
Publication Date Dec 31, 2012
Print ISSN 1359-7345
Electronic ISSN 1364-548X
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 48
Issue 8
Pages 1129-1131
Keywords Materials Chemistry; Electronic, Optical and Magnetic Materials; General Chemistry; Surfaces, Coatings and Films; Metals and Alloys; Ceramics and Composites; Catalysis
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