Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

Redshaw, Carl; Elsegood, Mark R. J.; Wright, Joseph A.; Baillie-Johnson, Hugo; Yamato, Takehiko; Giovanni, Stephen De; Mueller, Anja

Abstract

Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.

Citation

Redshaw, C., Elsegood, M. R. J., Wright, J. A., Baillie-Johnson, H., Yamato, T., Giovanni, S. D., & Mueller, A. (2012). Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene. Chemical communications : Chem comm / the Royal Society of Chemistry, 48(8), 1129-1131. https://doi.org/10.1039/c2cc16480a

• Journal Article Type: Article
• Acceptance Date: Nov 23, 2011
• Online Publication Date: Nov 24, 2011
• Publication Date: Dec 31, 2012
• Journal: CHEMICAL COMMUNICATIONS
• Print ISSN: 1359-7345
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 48
• Issue: 8
• Pages: 1129-1131
• DOI: https://doi.org/10.1039/c2cc16480a
• Keywords: Materials Chemistry; Electronic, Optical and Magnetic Materials; General Chemistry; Surfaces, Coatings and Films; Metals and Alloys; Ceramics and Composites; Catalysis
• Public URL: https://hull-repository.worktribe.com/output/418032