Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy

Frese, Josef W. A.; Redshaw, Carl; Elsegood, Mark R.J.; Frese, Josef W.A.; Ashby, Shane; Chao, Yimin; Mueller, Anja

doi:10.1039/c2cc32060f

Authors

Josef W. A. Frese

Professor Carl Redshaw C.Redshaw@hull.ac.uk
Professor of Inorganic Materials Chemistry and REF Lead for Chemistry

Mark R.J. Elsegood

Josef W.A. Frese

Shane Ashby

Yimin Chao

Anja Mueller

Abstract

Two hexanuclear zinc complexes have been structurally characterized, and evaluation against several cells showed selective toxicity. Cellular uptake revealed a non-specific process, resulting in accumulation within the cell cytoplasm. © 2012 The Royal Society of Chemistry.

Citation

Redshaw, C., Elsegood, M. R., Frese, J. W., Ashby, S., Chao, Y., & Mueller, A. (2012). Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy. Chemical communications : Chem comm / the Royal Society of Chemistry, 48(53), 6627. https://doi.org/10.1039/c2cc32060f

Journal Article Type	Article
Acceptance Date	Dec 31, 2012
Online Publication Date	Apr 16, 2012
Publication Date	2012
Journal	CHEMICAL COMMUNICATIONS
Print ISSN	1359-7345
Electronic ISSN	1364-548X
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	48
Issue	53
Pages	6627
DOI	https://doi.org/10.1039/c2cc32060f
Keywords	Materials Chemistry; Electronic, Optical and Magnetic Materials; General Chemistry; Surfaces, Coatings and Films; Metals and Alloys; Ceramics and Composites; Catalysis
Public URL	https://hull-repository.worktribe.com/output/418033
Publisher URL	http://pubs.rsc.org/en/Content/ArticleLanding/2012/CC/c2cc32060f#!divAbstract