Synthesis of 4-Alkyl-2′′, 3′′ difluoro terphenyl nitrile using coupling reactions

Lewis, Robert; Kayani, Zohra N.; Lewis, Robert A.; Naseem, Shahzad

Abstract

Study of chirality in liquid crystals is one of the most interesting areas of liquid crystal science. Liquid crystallineterphenyls with two lateral fluoro substituent and alkyl substituent in the 4- have been synthesised. Convergentapproach was applied which involved the use of arylboronic acids and aryl halides in palladium-catalysedcross-coupling reactions. All the diifluoroterphenyls generate the smectic C phase. Mixture of 4-Alkyl-2′′,3difluoro terphenyl nitrile in achiral host mixture HM1 generates ferroelectric liquid crystal properties.Ferroelectric properties were found to be highly dependent upon the relative lengths of the alkyl chainattached to chiral dopant. The compounds were studied using optical polarisation microscopy, differentialscanning calorimetric, nuclear magnetic resonance, and Instec elecro-optical device to find ferroelectric liquidcrystal properties.

Citation

Kayani, Z. N., Lewis, R. A., & Naseem, S. (2012). Synthesis of 4-Alkyl-2′′, 3′′ difluoro terphenyl nitrile using coupling reactions. Journal of Molecular Liquids, 175, 72-84. https://doi.org/10.1016/j.molliq.2012.08.012

• Journal Article Type: Article
• Acceptance Date: Aug 12, 2012
• Online Publication Date: Sep 6, 2012
• Publication Date: 2012-11
• Journal: Journal of Molecular Liquids
• Print ISSN: 0167-7322
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 175
• Pages: 72-84
• DOI: https://doi.org/10.1016/j.molliq.2012.08.012
• Keywords: Terphenyls; Convergent approach; Host mixture; Chiral dopant; Ferroelectric liquid crystal
• Public URL: https://hull-repository.worktribe.com/output/418042
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S016773221200298X