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Interfacing Living Unicellular Algae Cells with Biocompatible Polyelectrolyte-Stabilised Magnetic Nanoparticles

Fakhrullin, Rawil F.; Shlykova, Lubov V.; Zamaleeva, Alsu I.; Nurgaliev, Danis K.; Osin, Yuri N.; García-Alonso, Javier; Paunov, Vesselin N.

Authors

Rawil F. Fakhrullin

Lubov V. Shlykova

Alsu I. Zamaleeva

Danis K. Nurgaliev

Yuri N. Osin

Javier García-Alonso



Abstract

Green algae are a promising platform for the development of biosensors and bioelectronic devices. Here we report a reliable single-step technique for the functionalisation of living unicellular green algae Chlorella pyrenoidosa with biocompatible 15nm superparamagnetic nanoparticles stabilised with poly(allylamine hydrochloride). The magnetised algae cells can be manipulated and immobilised using external permanent magnets. The distribution of the nanoparticles on the cell walls of C. pyrenoidosa was studied by optical and fluorescence microscopy, TEM, SEM and EDX spectroscopy. The viability and the magnetic properties of the magnetised algae are studied in comparison with the native cells. The technique may find a number of potential applications in biotechnology and bioelectronics.

Journal Article Type Article
Publication Date Oct 8, 2010
Journal MACROMOLECULAR BIOSCIENCE
Print ISSN 1616-5187
Electronic ISSN 1616-5195
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 10
Issue 10
Pages 1257-1264
APA6 Citation Fakhrullin, R. F., Shlykova, L. V., Zamaleeva, A. I., Nurgaliev, D. K., Osin, Y. N., García-Alonso, J., & Paunov, V. N. (2010). Interfacing Living Unicellular Algae Cells with Biocompatible Polyelectrolyte-Stabilised Magnetic Nanoparticles. Macromolecular bioscience, 10(10), 1257-1264. https://doi.org/10.1002/mabi.201000161
DOI https://doi.org/10.1002/mabi.201000161
Keywords encapsulation; magnetic functionalization; polyelectrolytes; unicellular algae; viability
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