Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair

Barakat, Hashem M.; Shahin, Yousef; Khan, Junaid A.; McCollum, Peter T.; Chetter, Ian C.

Abstract

ObjectiveTo determine whether resting pre-operative left ventricular ejection fraction (LVEF) estimated by multiple gated acquisition scanning (MUGA) predicts long-term survival in patients undergoing elective abdominal aortic aneurysm (AAA) repair. Methods A retrospective study of MUGA scans which were performed to estimate pre-operative resting LVEF in 127 patients [106 (83%) males, mean age 74±7.6years] who underwent elective AAA repair over a period of 4years from March 2007. We compared outcomes and long-term survival between patients who had a pre-operative LVEF≤40% (Group 1, n=60) and LVEF>40% (Group 2, n=67). Results Overall 19 (15%) patients died during the follow-up period (13 patients in group 1 and 6 patients in group 2). 30-day mortality was 8%. There was no significant difference between group 1 and 2 in terms of patients' mean age or median length of hospital stay (8days for both groups, p=0.61). However, group 2 had more females than group 1(18 vs. 3, p=0.001). Median survival for patients in group 2 was significantly higher than patients in group 1 (1,258days vs. 1,000days, p=0.03). In a Cox regression model which included age, sex, smoking status and LVEF as covariates, only smoking status and LVEF predicted survival [Hazard ratio (HR)=1.06, p=0.04 and HR=0.93, p=0.00, respectively]. Conclusion This study shows that there is a role for pre-operative MUGA scan assessment of resting LVEF in predicting long-term survival post elective AAA repair and that the lower the pre-operative LVEF the poorer the long-term outcome.

Citation

Barakat, H. M., Shahin, Y., Khan, J. A., McCollum, P. T., & Chetter, I. C. (2013). Role of pre-operative multiple gated acquisition scanning in predicting long-term outcome in patients undergoing elective abdominal aortic aneurysm repair. World Journal of Surgery, 37(5), 1169-1173. https://doi.org/10.1007/s00268-013-1939-3

• Journal Article Type: Article
• Acceptance Date: Feb 1, 2013
• Online Publication Date: Feb 12, 2013
• Publication Date: 2013-05
• Journal: World Journal of Surgery
• Print ISSN: 0364-2313
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 37
• Issue: 5
• Pages: 1169-1173
• DOI: https://doi.org/10.1007/s00268-013-1939-3
• Keywords: Surgery
• Public URL: https://hull-repository.worktribe.com/output/432584