A ratiometric Al³⁺ ion probe based on the coumarin-quinoline FRET system

Zhu, Qin; Li, Li; Mu, Lan; Zeng, Xi; Redshaw, Carl; Wei, Gang

Abstract

A coumarin-quinoline based fluorescence resonance energy transfer (FRET) system (TCQ) has been synthesized and employed as a ratiometric fluorescence probe. The selective fluorescent response of the probe TCQ toward Al³⁺ was devised by employing a quinoline moiety as a FRET energy donor with a coumarin moiety as an energy acceptor. The quinoline emission at 390 nm decreased and the coumarin emission at 480 nm increased concurrently on addition of Al³⁺ under excitation wavelength at 253 nm. The TCQ probe exhibited high selectivity for Al³⁺ as compared to other tested metal ions and the ratiometric sensing of Al³⁺ was determined by plotting the fluorescence intensity ratio at 480 nm and 390 nm versus Al³⁺ ion concentration. Moreover, test strips based on TCQ were fabricated, which were found to act as a convenient and efficient Al³⁺ ion detection kit. Furthermore, this system has been used for imaging of Al³⁺ in living cells.

Citation

Zhu, Q., Li, L., Mu, L., Zeng, X., Redshaw, C., & Wei, G. (2016). A ratiometric Al³⁺ ion probe based on the coumarin-quinoline FRET system. Journal of Photochemistry and Photobiology A: Chemistry, 328, 217-224. https://doi.org/10.1016/j.jphotochem.2016.06.006

• Journal Article Type: Article
• Acceptance Date: Nov 4, 2016
• Online Publication Date: Jun 7, 2016
• Publication Date: Sep 1, 2016
• Deposit Date: Nov 17, 2016
• Publicly Available Date: Nov 23, 2017
• Journal: Journal of photochemistry and photobiology A : Chemistry
• Print ISSN: 1010-6030
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 328
• Pages: 217-224
• DOI: https://doi.org/10.1016/j.jphotochem.2016.06.006
• Keywords: Coumarin, Quinoline, FRET, Ratiometric flourescent probe, Al³⁺
• Public URL: https://hull-repository.worktribe.com/output/445242
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S1010603016302465
• Additional Information: Authors' accepted manuscript of article published in: Journal of photochemistry and photobiology A : Chemistry, 2016, v.328.