This patient is not breathing properly: is this COPD, heart failure, or neither?

Pellicori, Pierpaolo; Salekin, Damien; Pan, Daniel; Clark, Andrew L.

Abstract

© 2017 Informa UK Limited, trading as Taylor & Francis Group. Introduction: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are two common, heterogeneous, long-term illnesses which cause significant morbidity and mortality. Although they both present with breathlessness, they are treated differently. Treatment of COPD focuses mainly on relieving short-term breathlessness, whilst treatment of HF has focused on long term morbidity and mortality. Areas covered: In this review, we aim to highlight the diagnostic challenges in distinguishing COPD from HF. We also explore the implications of their overlap, and the use of biomarkers and treatments for HF in patients with COPD to improve long-term outcomes. Expert commentary: Cardiovascular morbidity and mortality amongst patients with COPD is substantial. Approaches which identify patients with COPD at highest cardiovascular risk may therefore be helpful. A trial targeting those patients with COPD and raised natriuretic peptide levels might be the way to test whether cardiovascular medication has anything to offer the respiratory patient.

Citation

Pellicori, P., Salekin, D., Pan, D., & Clark, A. L. (2017). This patient is not breathing properly: is this COPD, heart failure, or neither?. Expert Review of Cardiovascular Therapy, 15(5), 389-396. https://doi.org/10.1080/14779072.2017.1317592

• Acceptance Date: Apr 11, 2017
• Online Publication Date: Apr 17, 2017
• Publication Date: May 4, 2017
• Deposit Date: Nov 10, 2017
• Publicly Available Date: Apr 18, 2018
• Journal: Expert Review of Cardiovascular therapy
• Print ISSN: 1477-9072
• Publisher: Taylor and Francis
• Peer Reviewed: Peer Reviewed
• Volume: 15
• Issue: 5
• Pages: 389-396
• DOI: https://doi.org/10.1080/14779072.2017.1317592
• Keywords: COPD; Heart failure; Naturetic peptides; Review; Therapy
• Public URL: https://hull-repository.worktribe.com/output/456451
• Publisher URL: http://www.tandfonline.com/doi/abs/10.1080/14779072.2017.1317592?tab=permissions&scroll=top
• Additional Information: This is the accepted version of an article published in Expert Review of Cardiovascular Therapy, 2017. The published version is available at the DOI link.
• Contract Date: Nov 10, 2017