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Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019

Momtazmanesh, Sara; Moghaddam, Sahar Saeedi; Ghamari, Seyyed Hadi; Rad, Elaheh Malakan; Rezaei, Negar; Shobeiri, Parnian; Aali, Amirali; Abbasi-Kangevari, Mohsen; Abbasi-Kangevari, Zeinab; Abdelmasseh, Michael; Abdoun, Meriem; Abdulah, Deldar Morad; Md Abdullah, Abu Yousuf; Abedi, Aidin; Abolhassani, Hassan; Abrehdari-Tafreshi, Zahra; Achappa, Basavaprabhu; Adane, Denberu Eshetie Adane; Adane, Tigist Demssew; Addo, Isaac Yeboah; Adnan, Mohammad; Adnani, Qorinah Estiningtyas Sakilah; Ahmad, Sajjad; Ahmadi, Ali; Ahmadi, Keivan; Ahmed, Ali; Ahmed, Ayman; Rashid, Tarik Ahmed; Al Hamad, Hanadi; Alahdab, Fares; Alemayehu, Astawus; Alif, Sheikh Mohammad; Aljunid, Syed Mohamed; Almustanyir, Sami; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Dehkordi, Javad Aminian; Amir-Behghadami, Mehrdad; Ancuceanu, Robert; Andrei, Catalina Liliana; Andrei, Tudorel; Antony, Catherine M.; Anyasodor, Anayochukwu Edward; Arabloo, Jalal; Arulappan, Judie; Ashraf, Tahira; Athari, Seyyed Shamsadin; Attia, Engi F.;...

Authors

Sara Momtazmanesh

Sahar Saeedi Moghaddam

Seyyed Hadi Ghamari

Elaheh Malakan Rad

Negar Rezaei

Parnian Shobeiri

Amirali Aali

Mohsen Abbasi-Kangevari

Zeinab Abbasi-Kangevari

Michael Abdelmasseh

Meriem Abdoun

Deldar Morad Abdulah

Abu Yousuf Md Abdullah

Aidin Abedi

Hassan Abolhassani

Zahra Abrehdari-Tafreshi

Basavaprabhu Achappa

Denberu Eshetie Adane Adane

Tigist Demssew Adane

Isaac Yeboah Addo

Mohammad Adnan

Qorinah Estiningtyas Sakilah Adnani

Sajjad Ahmad

Ali Ahmadi

Keivan Ahmadi

Ali Ahmed

Ayman Ahmed

Tarik Ahmed Rashid

Hanadi Al Hamad

Fares Alahdab

Astawus Alemayehu

Sheikh Mohammad Alif

Syed Mohamed Aljunid

Sami Almustanyir

Khalid A. Altirkawi

Nelson Alvis-Guzman

Javad Aminian Dehkordi

Mehrdad Amir-Behghadami

Robert Ancuceanu

Catalina Liliana Andrei

Tudorel Andrei

Catherine M. Antony

Anayochukwu Edward Anyasodor

Jalal Arabloo

Judie Arulappan

Tahira Ashraf

Seyyed Shamsadin Athari

Engi F. Attia

Meshesha Tsegazeab Ayele

Sina Azadnajafabad

Abraham Samuel Babu

Sara Bagherieh

Ovidiu Constantin Baltatu

MacIej Banach

Mainak Bardhan

Francesco Barone-Adesi

Amadou Barrow

Saurav Basu

Nebiyou Simegnew Bayileyegn

Isabela M. Bensenor

Nikha Bhardwaj

Pankaj Bhardwaj

Ajay Nagesh Bhat

Krittika Bhattacharyya

Souad Bouaoud

Dejana Braithwaite

Michael Brauer

Muhammad Hammad Butt

Zahid A. Butt

Daniela Calina

Luis Alberto Cámera

Gashaw Sisay Chanie

Periklis Charalampous

Vijay Kumar Chattu

Odgerel Chimed-Ochir

Dinh Toi Chu

Aaron J. Cohen

Natália Cruz-Martins

Omid Dadras

Aso Mohammad Darwesh

Saswati Das

Sisay Abebe Debela

Laura Delgado-Ortiz

Diriba Dereje

Mostafa Dianatinasab

Nancy Diao

Daniel Diaz

Lankamo Ena Digesa

Gebisa Dirirsa

Paul Narh Doku

Deepa Dongarwar

Abdel Douiri

Haneil Larson Dsouza

Ebrahim Eini

Michael Ekholuenetale

Temitope Cyrus Ekundayo

Ahmed Elabbas Mustafa Elagali

Muhammed Elhadi

Daniel Berhanie Enyew

Ryenchindorj Erkhembayar



Abstract

Background: Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-communicable diseases by 2030. We provided global, regional, and national estimates of the burden of CRDs and their attributable risks from 1990 to 2019. Methods: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated mortality, years lived with disability, years of life lost, disability-adjusted life years (DALYs), prevalence, and incidence of CRDs, i.e. chronic obstructive pulmonary disease (COPD), asthma, pneumoconiosis, interstitial lung disease and pulmonary sarcoidosis, and other CRDs, from 1990 to 2019 by sex, age, region, and Socio-demographic Index (SDI) in 204 countries and territories. Deaths and DALYs from CRDs attributable to each risk factor were estimated according to relative risks, risk exposure, and the theoretical minimum risk exposure level input. Findings: In 2019, CRDs were the third leading cause of death responsible for 4.0 million deaths (95% uncertainty interval 3.6–4.3) with a prevalence of 454.6 million cases (417.4–499.1) globally. While the total deaths and prevalence of CRDs have increased by 28.5% and 39.8%, the age-standardised rates have dropped by 41.7% and 16.9% from 1990 to 2019, respectively. COPD, with 212.3 million (200.4–225.1) prevalent cases, was the primary cause of deaths from CRDs, accounting for 3.3 million (2.9–3.6) deaths. With 262.4 million (224.1–309.5) prevalent cases, asthma had the highest prevalence among CRDs. The age-standardised rates of all burden measures of COPD, asthma, and pneumoconiosis have reduced globally from 1990 to 2019. Nevertheless, the age-standardised rates of incidence and prevalence of interstitial lung disease and pulmonary sarcoidosis have increased throughout this period. Low- and low-middle SDI countries had the highest age-standardised death and DALYs rates while the high SDI quintile had the highest prevalence rate of CRDs. The highest deaths and DALYs from CRDs were attributed to smoking globally, followed by air pollution and occupational risks. Non-optimal temperature and high body-mass index were additional risk factors for COPD and asthma, respectively. Interpretation: Albeit the age-standardised prevalence, death, and DALYs rates of CRDs have decreased, they still cause a substantial burden and deaths worldwide. The high death and DALYs rates in low and low-middle SDI countries highlights the urgent need for improved preventive, diagnostic, and therapeutic measures. Global strategies for tobacco control, enhancing air quality, reducing occupational hazards, and fostering clean cooking fuels are crucial steps in reducing the burden of CRDs, especially in low- and lower-middle income countries. Funding: Bill & Melinda Gates Foundation.

Citation

Momtazmanesh, S., Moghaddam, S. S., Ghamari, S. H., Rad, E. M., Rezaei, N., Shobeiri, P., …Soyiri, I. (2023). Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019. EClinicalMedicine, 59, Article 101936. https://doi.org/10.1016/j.eclinm.2023.101936

Journal Article Type Article
Acceptance Date Mar 14, 2023
Online Publication Date Apr 25, 2023
Publication Date May 1, 2023
Deposit Date Jun 20, 2024
Publicly Available Date Jun 28, 2024
Journal eClinicalMedicine
Electronic ISSN 2589-5370
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 59
Article Number 101936
DOI https://doi.org/10.1016/j.eclinm.2023.101936
Keywords Asthma; Chronic obstructive pulmonary disease; Epidemiology; Interstitial lung disease; Lung disease; Morbidity; Mortality; Pneumoconiosis; Pulmonary emphysema
Public URL https://hull-repository.worktribe.com/output/4713305

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