Water-in-water emulsions based on incompatible polymers and stabilized by triblock copolymers-templated polymersomes

Buzza, D. Martin A; Fletcher, Paul D I; Georgiou, Theoni K.; Ghasdian, Negar

Abstract

Aqueous solutions containing a mixture of polyethylene glycol (PEG) and dextran homopolymers form an aqueous two-phase system which can be emulsified to give a water-in-water emulsion. We show how these emulsions can be stabilized using triblock polymers containing poly[poly(ethylene glycol) methyl ether methacrylate] (PEGMA), poly (n-butyl methacrylate) (BuMA), and poly[2-(dimethylamino) ethyl methacrylate] (DMAEMA) blocks of general structure Pp-Bb-Dd, in which the middle BuMA block is hydrophobic. Low-energy input stirring of mixtures containing equal volumes of PEG- and dex-rich aqueous phases plus 1 wt % of Pp-Bb-Dd stabilizer all form dex-in-PEG emulsions (for the range of Pp-Bb-Dd triblock polymers used here) which have a polymersome-like structure. In favorable cases, the emulsion drop (or templated polymersome) sizes are a few micrometers and are stable for periods in excess of 6 months. The emulsions can be inverted from dex-in-PEG to PEG-in-dex by increasing the volume fraction of dex-rich aqueous phase. We demonstrate that both high and low molecular weight fluorescent solutes “self-load” into either the dex- or PEG-rich regions and that solute mass transfer across the water–water interface occurs on a timescale of less than 1 min.

Citation

Buzza, D. M. A., Fletcher, P. D. I., Georgiou, T. K., & Ghasdian, N. (2013). Water-in-water emulsions based on incompatible polymers and stabilized by triblock copolymers-templated polymersomes. Langmuir : the ACS journal of surfaces and colloids, 29(48), 14804-14814. https://doi.org/10.1021/la403356j

• Journal Article Type: Article
• Acceptance Date: Sep 2, 2013
• Online Publication Date: Nov 22, 2013
• Publication Date: Dec 3, 2013
• Deposit Date: Jun 27, 2018
• Journal: Langmuir
• Print ISSN: 0743-7463
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 29
• Issue: 48
• Pages: 14804-14814
• DOI: https://doi.org/10.1021/la403356j
• Public URL: https://hull-repository.worktribe.com/output/896368
• Publisher URL: https://pubs.acs.org/doi/abs/10.1021/la403356j
• Contract Date: Jun 27, 2018