All Outputs (4)

Ohgata, the single Drosophila ortholog of human cereblon, regulates insulin signaling-dependent organismic growth (2016)
Journal Article
Wakabayashi, S., Sawamura, N., Voelzmann, A., Broemer, M., Asahi, T., & Hoch, M. (2016). Ohgata, the single Drosophila ortholog of human cereblon, regulates insulin signaling-dependent organismic growth. Journal of Biological Chemistry, 291(48), 25120-25132. https://doi.org/10.1074/jbc.M116.757823

Cereblon (CRBN) is a substrate receptor of the E3 ubiquitin ligase complex that is highly conserved in animals and plants. CRBN proteins have been implicated in various biological processes such as development, metabolism, learning, and memory format... Read More about Ohgata, the single Drosophila ortholog of human cereblon, regulates insulin signaling-dependent organismic growth.

A conceptual view at microtubule plus end dynamics in neuronal axons (2016)
Journal Article
Voelzmann, A., Hahn, I., Pearce, S. P., Sánchez-Soriano, N., & Prokop, A. (2016). A conceptual view at microtubule plus end dynamics in neuronal axons. Brain Research Bulletin, 126(3), 226-237. https://doi.org/10.1016/j.brainresbull.2016.08.006

Axons are the cable-like protrusions of neurons which wire up the nervous system. Polar bundles of microtubules (MTs) constitute their structural backbones and are highways for life-sustaining transport between proximal cell bodies and distal synapse... Read More about A conceptual view at microtubule plus end dynamics in neuronal axons.

Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking (2016)
Journal Article
Voelzmann, A., Okenve-Ramos, P., Qu, Y., Chojnowska-Monga, M., del Caño-Espinel, M., Prokop, A., & Sanchez-Soriano, N. (2016). Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking. eLife, 5, Article e14694. https://doi.org/10.7554/elife.14694

The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Ta... Read More about Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking.

Nuclear Drosophila CerS Schlank regulates lipid homeostasis via the homeodomain, independent of the lag1p motif (2016)
Journal Article
Voelzmann, A., Wulf, A. L., Eckardt, F., Thielisch, M., Brondolin, M., Pesch, Y. Y., …Hoch, M. (2016). Nuclear Drosophila CerS Schlank regulates lipid homeostasis via the homeodomain, independent of the lag1p motif. FEBS Letters, 590(7), 971-981. https://doi.org/10.1002/1873-3468.12125

Drosophila Ceramide Synthase (CerS) Schlank regulates both ceramide synthesis and fat metabolism. Schlank contains a catalytic lag1p motif and, like many CerS in other species, a homeodomain of unknown function. Here, we show that the Drosophila CerS... Read More about Nuclear Drosophila CerS Schlank regulates lipid homeostasis via the homeodomain, independent of the lag1p motif.