All Outputs (62)

Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis (2022)
Journal Article
Lv, X., Yin, L., Wu, W., Li, N., Zhang, R., Li, X., Jia, Q., Tan, J., Wang, P., Zheng, X., He, X., Huang, C., Li, D., Wang, Y., & Meng, Z. (2022). Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis. Journal of Healthcare Engineering, 2022, Article 7640405. https://doi.org/10.1155/2022/7640405

Purpose. Quantitative scintigraphy to evaluate salivary gland function changes in patients with differentiated thyroid cancer (DTC) after iodine-131 (131I) treatment. Methods. A total of 458 patients with DTC grouped by sex and age were included. Sal... Read More about Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis.

Simplification or simulation: power calculation in clinical trials (2021)
Journal Article
Huang, C., Li, P., & Martin, C. R. (2022). Simplification or simulation: power calculation in clinical trials. Contemporary clinical trials, 113, Article 106663. https://doi.org/10.1016/j.cct.2021.106663

Background and objectives: A justifiable sample size is essential at trial design stage. Generally this task is completed by forming the main research question into a statistical procedure and then implementing the published formulae or software pack... Read More about Simplification or simulation: power calculation in clinical trials.

Correction to: Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum (International Journal of Obesity, (2021), 45, 8, (1728-1739), 10.1038/s41366-021-00835-0) (2021)
Journal Article
Simpson, S. A., Coulman, E., Gallagher, D., Jewell, K., Cohen, D., Newcombe, R. G., Huang, C., Robles-Zurita, J. A., Busse, M., Owen-Jones, E., Duncan, D., Williams, N., Stanton, H., Avery, A., McIntosh, E., & Playle, R. (2022). Correction to: Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum (International Journal of Obesity, (2021), 45, 8, (1728-1739), 10.1038/s41366-021-00835-0). International journal of obesity, 46, Article 242. https://doi.org/10.1038/s41366-021-00976-2

The original version of this article unfortunately contained an error in an author name. Jose Antonio Robles should be changed to José Antonio Robles-Zurita. The authors apologize for the error. The original article has been corrected.

The prognostic value of respiratory symptoms and performance status in ambulatory cancer patients and unsuspected pulmonary embolism; analysis of an international, prospective, observational cohort study (2021)
Journal Article
Maraveyas, A., Kraaijpoel, N., Bozas, G., Huang, C., Mahé, I., Bertoletti, L., Bartels-Rutten, A., Beyer-Westendorf, J., Constans, J., Iosub, D., Couturaud, F., Muñoz, A. J., Biosca, M., Lerede, T., van Es, N., Di Nisio, M., Accassat, S., The UPE investigators, Aquilanti, S., Assaf, J. D., …Zumàrraga Cuesta, A. (2021). The prognostic value of respiratory symptoms and performance status in ambulatory cancer patients and unsuspected pulmonary embolism; analysis of an international, prospective, observational cohort study. Journal of thrombosis and haemostasis : JTH, 19(11), 2791-2800. https://doi.org/10.1111/jth.15489

Background: Optimal risk stratification of unsuspected pulmonary embolism (UPE) in ambulatory cancer patients (ACPs) remains unclear. Existing clinical predictive rules (CPRs) are derived from retrospective databases and have limitations. The UPE reg... Read More about The prognostic value of respiratory symptoms and performance status in ambulatory cancer patients and unsuspected pulmonary embolism; analysis of an international, prospective, observational cohort study.

The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations (2021)
Journal Article
Martin, C. R., Jones, C., Huang, C., Jomeen, J., Boubert, L., & Marshall, C. A. (in press). The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations. Journal of reproductive and infant psychology, https://doi.org/10.1080/02646838.2021.1931070

Objective: To examine the measurement model of the Tokophobia Severity Scale and consider issues of statistical power and sample size from the original instrument development study. Background: Fear of childbirth (FoC) and tokophobia represents an ar... Read More about The Tokophobia Severity Scale (TSS): measurement model, power and sample size considerations.

Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum (2021)
Journal Article
Robles, J. A., Simpson, S. A., Coulman, E., Gallagher, D., Jewell, K., Cohen, D., …Playle, R. (2021). Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum. International journal of obesity, 45(8), 1728-1739. https://doi.org/10.1038/s41366-021-00835-0

Objective: To assess whether a weight management intervention for pregnant women with obesity was effective in reducing body mass index (BMI) 12 months after giving birth. Methods: Pragmatic, cluster randomised controlled trial (RCT) with embedded co... Read More about Healthy eating and lifestyle in pregnancy (HELP): a cluster randomised trial to evaluate the effectiveness of a weight management intervention for pregnant women with obesity on weight at 12 months postpartum.

Do patient characteristics matter when calculating sample size for eczema clinical trials? (2021)
Journal Article
Howells, L., Gran, S., Chalmers, J. R., Stuart, B., Santer, M., Bradshaw, L., …Thomas, K. S. (2021). Do patient characteristics matter when calculating sample size for eczema clinical trials?. Skin Health and Disease, 1(3), Article e42. https://doi.org/10.1002/ski2.42

Background: The Patient-Oriented Eczema Measure (POEM) is the core outcome instrument recommended for measuring patient-reported atopic eczema symptoms in clinical trials. To ensure that the statistical significance of clinical trial results is meani... Read More about Do patient characteristics matter when calculating sample size for eczema clinical trials?.

Prostate cancer: unmet supportive and palliative care needs: national survey of patients and family carers (2021)
Journal Article
Johnson, M. J., Huang, C., Chen, H., Jones, L., & Twiddy, M. (2021). Prostate cancer: unmet supportive and palliative care needs: national survey of patients and family carers. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2021-003438

Objectives: Men living with prostate cancer have supportive and palliative needs. However, few studies detail unmet needs (vs quality of life measurement) or include data from those with advanced disease. We aimed to identify unmet needs of people li... Read More about Prostate cancer: unmet supportive and palliative care needs: national survey of patients and family carers.

Fear of childbirth measurement: appraisal of the content overlap of four instruments (2020)
Journal Article
Martin, C., Jones, C., Marshall, C. A., Huang, C., Reeve, J., Fleming, M. P., König, J., & Jomeen, J. (2022). Fear of childbirth measurement: appraisal of the content overlap of four instruments. Journal of reproductive and infant psychology, 40(4), 329-341. https://doi.org/10.1080/02646838.2020.1861226

Objective: To evaluate empirically the degree of content overlap between four self-report measures of fear of childbirth (FoC) identified as ‘best in class’ by a recent review. Background: FoC and tokophobia is an area of increasing clinical concern... Read More about Fear of childbirth measurement: appraisal of the content overlap of four instruments.

Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review) (2020)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Harwood, A., Ingle, L., Huang, C., & Chetter, I. C. (2020). Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review). The Cochrane database of systematic reviews, 2020(9), Article CD013407. https://doi.org/10.1002/14651858.CD013407.pub2

Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and... Read More about Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review).

Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. (2020)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Elizabeth Harwood, A., Ingle, L., Huang, C., & Chetter, I. C. (2020). Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. Cochrane Database of Systematic Reviews, Article CD013407. https://doi.org/10.1002/14651858.CD013407.pub2

Background
Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and narrowed. The most severe manifestation of PAD is critical limb ischaemia (CLI). Th... Read More about Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease..

Specialist alcohol inpatient treatment admissions and non-specialist hospital admissions for alcohol withdrawal in England: an inverse relationship (2020)
Journal Article
Phillips, T., Huang, C., Roberts, E., & Drummond, C. (2021). Specialist alcohol inpatient treatment admissions and non-specialist hospital admissions for alcohol withdrawal in England: an inverse relationship. Alcohol and Alcoholism, 56(1), 28-33. https://doi.org/10.1093/alcalc/agaa086

© The Author(s) 2020. Medical Council on Alcohol and Oxford University Press. AIMS: We assessed the relationship between specialist and non-specialist admissions for alcohol withdrawal since the introduction of the UK government Health and Social Car... Read More about Specialist alcohol inpatient treatment admissions and non-specialist hospital admissions for alcohol withdrawal in England: an inverse relationship.

The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis (2020)
Journal Article
Marshall, C., Jomeen, J., Huang, C., & Martin, C. (2020). The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 17(16), 1-19. https://doi.org/10.3390/ijerph17165778

Title: Systematic review and meta-analysis of the relationship between maternal personality disorder and early birth outcomes.
Background: Women with personality disorder are at risk of social and emotional problems which impact deleteriously on eve... Read More about The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis.

Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness (2020)
Journal Article
Ekström, M., Johnson, M. J., Huang, C., & Currow, D. C. (2020). Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness. European respiratory journal, 56(2), Article 1902202. https://doi.org/10.1183/13993003.02202-2019

Copyright ©ERS 2020. BACKGROUND: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9 mm on a 100-mm visual analogue scale (VAS). We aimed to determine M... Read More about Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness.

Letter in Response to Grobler AC, Lee K. Intention-To-Treat Analyses for Randomized Controlled Trials in Hospice/Palliative Care Enhanced by Principled Methods to Handle Missing Data (2020)
Journal Article
Huang, C., Kochovska, S., & Currow, D. C. (2020). Letter in Response to Grobler AC, Lee K. Intention-To-Treat Analyses for Randomized Controlled Trials in Hospice/Palliative Care Enhanced by Principled Methods to Handle Missing Data. Journal of pain and symptom management, 60(4), e30-e31. https://doi.org/10.1016/j.jpainsymman.2020.07.004

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., Long, J., Rooms, M., & Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial (2020)
Journal Article
Nicholls, A. R., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., Cope, E., & Ntoumanis, N. (2020). The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial. International Journal of Drug Policy, 82, Article 102820. https://doi.org/10.1016/j.drugpo.2020.102820

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results.
Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial.

The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial (2020)
Journal Article
Nicholls, A., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., Cope, E., & Ntoumanis, N. (in press). The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial. International Journal of Drug Policy,

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results.
Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial.

A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin (2020)
Journal Article
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., Evans, L., Lester, J., Jagdev, S., Casbard, A., Huang, C., Madden, T. A., & Griffiths, G. (2020). A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin. BJU international, 126(2), 292-299. https://doi.org/10.1111/bju.15096

Objectives
To assess the efficacy and tolerability of the dual epidermal growth factor receptor/vascular endothelial growth factor receptor inhibitor, vandetanib, in combination with carboplatin and gemcitabine in the first‐line treatment of patient... Read More about A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin.

Development and evaluation of a screening tool to aid the diagnosis of a cluster headache (2020)
Journal Article
Buture, A., Boland, J. W., Dikomitis, L., Huang, C., & Ahmed, F. (2020). Development and evaluation of a screening tool to aid the diagnosis of a cluster headache. Brain Sciences, 10(2), Article 77. https://doi.org/10.3390/brainsci10020077

Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of... Read More about Development and evaluation of a screening tool to aid the diagnosis of a cluster headache.