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All Outputs (2)

Identification of the Interacting Domains Between Tissue Factor and β1-Integrin and the Signalling Properties of the Two Fibronectin-like Domains of Tissue Factor (2025)
Journal Article
Featherby, S. J., Faulkner, E. C., Maraveyas, A., & Ettelaie, C. (2025). Identification of the Interacting Domains Between Tissue Factor and β1-Integrin and the Signalling Properties of the Two Fibronectin-like Domains of Tissue Factor. Cancers, 17(4), Article 644. https://doi.org/10.3390/cancers17040644

Background: Interactions between tissue factor (TF) and β1-integrin induce cell signals, but the molecular mechanisms are not completely understood. The extracellular domain of TF and EGF4-βTD domains of β1-integrin were hypothesised to be the most l... Read More about Identification of the Interacting Domains Between Tissue Factor and β1-Integrin and the Signalling Properties of the Two Fibronectin-like Domains of Tissue Factor.

Tissue factor signalling modifies the expression and regulation of G1/S checkpoint regulators: Implications during injury and prolonged inflammation (2024)
Journal Article
Featherby, S., Faulkner, E., & Ettelaie, C. (2025). Tissue factor signalling modifies the expression and regulation of G1/S checkpoint regulators: Implications during injury and prolonged inflammation. Molecular Medicine Reports, 31(2), Article 39. https://doi.org/10.3892/mmr.2024.13404

Tissue factor (TF) possesses additional physiological functions beyond initiating the coagulation cascade. Cellular signals initiated by cellular TF or on contact with TF-containing microvesicles, contribute to wound healing through regulating a numb... Read More about Tissue factor signalling modifies the expression and regulation of G1/S checkpoint regulators: Implications during injury and prolonged inflammation.