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Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos (2020)
Journal Article
Arabeyyat, Z. H., Al-Awady, M. J., Greenway, G. M., Paunov, V. N., & Rotchell, J. M. (2020). Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos. SN Applied Sciences, 2(7), Article 1312. https://doi.org/10.1007/s42452-020-3137-x

We investigated the effects of short-term exposure of bare TiO2NPs and polyelectrolyte-coated TiO2NPs in the 5–25nm size range, at relatively high concentrations (of 500 and 1000mg/L) under light or dark conditions, in D. rerio embryos. The biologica... Read More about Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos.

Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification (2011)
Journal Article
Hardege, J., Rotchell, J., Terschak, J., & Greenway, G. (2011). Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification. Trends in Analytical Chemistry, 30(8), 1320-1326. https://doi.org/10.1016/j.trac.2011.07.004

Changing ocean-carbonate chemistry caused by oceanic uptake of anthropogenic atmospheric carbon dioxide leads to the formation of carbonic acid, thus lowering the pH of the sea with predictions of a decrease from current levels at 8.15 to 7.82 by the... Read More about Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification.

Biological responses to contaminants in the Humber Estuary: disentangling complex relationships (2011)
Journal Article
García-Alonso, J., Greenway, G., Munshi, A., Gómez, J., Mazik, K., Knight, A. W., Hardege, J., & Elliott, M. (2011). Biological responses to contaminants in the Humber Estuary: disentangling complex relationships. Marine environmental research, 71(4), 295-303. https://doi.org/10.1016/j.marenvres.2011.02.004

Due to the ecological importance of estuaries, it is necessary to understand the biological effects that potentially toxic contaminants induce in bioindicator species. A key aspect is whether effects at lower levels of biological organisation transfe... Read More about Biological responses to contaminants in the Humber Estuary: disentangling complex relationships.

Development of a real-world direct interface for integrated DNA extraction and amplification in a microfluidic device (2010)
Journal Article
Shaw, K. J., Joyce, D., Docker, P. T., Dyer, C. E., Greenway, G. M., Greenman, J., & Haswell, S. J. (2011). Development of a real-world direct interface for integrated DNA extraction and amplification in a microfluidic device. Lab on a chip, 11(3), 443-448. https://doi.org/10.1039/c0lc00346h

Integrated DNA extraction and amplification have been carried out in a microfluidic device using electro-osmotic pumping (EOP) for fluidic control. All the necessary reagents for performing both DNA extraction and polymerase chain reaction (PCR) ampl... Read More about Development of a real-world direct interface for integrated DNA extraction and amplification in a microfluidic device.

Microscreening toxicity system based on living magnetic yeast and gradient chips (2010)
Journal Article
García-Alonso, J., Fakhrullin, R. F., Paunov, V. N., Shen, Z., Hardege, J. D., Pamme, N., Haswell, S. J., & Greenway, G. M. (2011). Microscreening toxicity system based on living magnetic yeast and gradient chips. Analytical and Bioanalytical Chemistry, 400(4), 1009-1013. https://doi.org/10.1007/s00216-010-4241-3

There is an increasing demand for easy and cost-effective methods to screen the toxicological impact of the growing number of chemical mixtures being generated by industry. Such a screening method has been developed using viable, genetically modified... Read More about Microscreening toxicity system based on living magnetic yeast and gradient chips.

Simple practical approach for sample loading prior to DNA extraction using a silica monolith in a microfluidic device (2009)
Journal Article
Shaw, K. J., Docker, P. T., Haswell, S. J., Joyce, D. A., Dyer, C. E., Greenman, J., & Greenway, G. M. (2009). Simple practical approach for sample loading prior to DNA extraction using a silica monolith in a microfluidic device. Lab on a chip, 9(23), 3430-3432. https://doi.org/10.1039/b913309g

A novel DNA loading methodology is presented for performing DNA extraction on a microfluidic system. DNA in a chaotropic salt solution was manually loaded onto a silica monolith orthogonal to the subsequent flow of wash and elution solutions. DNA was... Read More about Simple practical approach for sample loading prior to DNA extraction using a silica monolith in a microfluidic device.

A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds (2008)
Journal Article
García-Alonso, J., Greenway, G. M., Hardege, J. D., & Haswell, S. J. (2009). A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds. Biosensors & bioelectronics, 24(5), 1508-1511. https://doi.org/10.1016/j.bios.2008.07.074

A microfluidic chip has been developed to enable the screening of chemicals for environmental toxicity. The microfluidic approach offers several advantages over macro-scale systems for toxicity screening, including low cost and flexibility in design.... Read More about A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds.