Development of New Peptidomimetic NADPH Oxidase Inhibitors with Antithrombotic Properties
(2024)
Journal Article
Scalia, E., Chirco, A., Calugi, L., Lenci, E., Pagano, P. J., Pula, G., & Trabocchi, A. (2024). Development of New Peptidomimetic NADPH Oxidase Inhibitors with Antithrombotic Properties. ChemMedChem, 19(19), Article e202400330. https://doi.org/10.1002/cmdc.202400330
The ability of synthetic peptides inhibitors of NOX1 to effectively block the production of ROS by the enzyme was studied with different methodologies. Specifically, taking advantage of our understanding of the active epitope of the regulatory NOX1 s... Read More about Development of New Peptidomimetic NADPH Oxidase Inhibitors with Antithrombotic Properties.