All Outputs (2)

Hyperactivity and Pro-inflammatory Functions of Platelets in Diabetes (2025)
Journal Article
Pula, G., & Greaves, J. (2025). Hyperactivity and Pro-inflammatory Functions of Platelets in Diabetes. Frontiers in Bioscience-Landmark, 30(1), Article 26190. https://doi.org/10.31083/FBL26190

Cardiovascular complications claim the lives of up to 70% of patients with diabetes mellitus (DM). The mechanisms increasing cardiovascular risk in DM remain to be fully understood and successfully addressed. Nonetheless, there is increasing evidence... Read More about Hyperactivity and Pro-inflammatory Functions of Platelets in Diabetes.

Development of New Peptidomimetic NADPH Oxidase Inhibitors with Antithrombotic Properties (2024)
Journal Article
Scalia, E., Chirco, A., Calugi, L., Lenci, E., Pagano, P. J., Pula, G., & Trabocchi, A. (2024). Development of New Peptidomimetic NADPH Oxidase Inhibitors with Antithrombotic Properties. ChemMedChem, 19(19), Article e202400330. https://doi.org/10.1002/cmdc.202400330

The ability of synthetic peptides inhibitors of NOX1 to effectively block the production of ROS by the enzyme was studied with different methodologies. Specifically, taking advantage of our understanding of the active epitope of the regulatory NOX1 s... Read More about Development of New Peptidomimetic NADPH Oxidase Inhibitors with Antithrombotic Properties.