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Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure (2022)
Journal Article
Kazmi, S., Kambhampati, C., Cleland, J., Cuthbert, J., Kazmi, K. S., Pellicori, P., …Clark, A. L. (2022). Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure. ESC Heart Failure, https://doi.org/10.1002/ehf2.14028

Aims: Risk changes with the progression of disease and the impact of treatment. We developed a dynamic risk stratification Markov chain model using artificial intelligence in patients with chronic heart failure (CHF). Methods and results: We describe... Read More about Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure.

Clinical and prognostic association of total atrial conduction time in patients with heart failure: A report from studies investigating co-morbidities aggravating heart failure (2019)
Journal Article
Nuzzi, V., Pellicori, P., Nikolaidou, T., Kallvikbacka-Bennett, A., Torromeo, C., Barilla, F., …Clark, A. L. (2019). Clinical and prognostic association of total atrial conduction time in patients with heart failure: A report from studies investigating co-morbidities aggravating heart failure. Journal of Cardiovascular Medicine, 20(7), 442-449. https://doi.org/10.2459/JCM.0000000000000802

Background The total atrial conduction time can be measured as the time from the onset of the P wave on the ECG to the peak of the A wave recorded at the mitral annulus using tissue Doppler imaging (A'; P-A'TDI); when prolonged, it might predict inci... Read More about Clinical and prognostic association of total atrial conduction time in patients with heart failure: A report from studies investigating co-morbidities aggravating heart failure.

Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure (2018)
Journal Article
Zhang, J., Pellicori, P., Pan, D., Dierckx, R., Clark, A. L., & Cleland, J. (2018). Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure. International journal of cardiology, 269, 196-200. https://doi.org/10.1016/j.ijcard.2018.06.070

Background
Prognostic models for patients with chronic heart failure are generally based on a single assessment but treatment is often given with the intention of changing risk; re- evaluation of risk is an important aspect of care. The prognostic va... Read More about Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure.

Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling (2017)
Journal Article
Zhang, J., Wong, K., Clark, A. L., & Cleland, J. G. (2017). Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling. International journal of cardiology, 233, 67-72. https://doi.org/10.1016/j.ijcard.2017.01.127

Background The relation between changes in NT-proBNP and renal function has commonly been studied using multiple regressions, which may ignore the complexity of relations between related variables. Methods and results Data were collected from patient... Read More about Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling.