Seizure control by decanoic acid through direct AMPA receptor inhibition
(2015)
Journal Article
Chang, P., Augustin, K., Boddum, K., Williams, S., Sun, M., Terschak, J. A., Hardege, J. D., Chen, P. E., Walker, M. C., & Williams, R. S. (2016). Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain, 139(2), 431-443. https://doi.org/10.1093/brain/awv325
The medium chain triglyceride ketogenic diet is an established treatment for drug-resistant epilepsy that increases plasma levels of decanoic acid and ketones. Recently, decanoic acid has been shown to provide seizure control in vivo, yet its mechani... Read More about Seizure control by decanoic acid through direct AMPA receptor inhibition.